ROLE OF SCHMIDT-LANTERMAN INCISURES IN WALLERIAN DEGENERATION .2. ELECTRON-MICROSCOPIC STUDY

ROLE OF SCHMIDT-LANTERMAN INCISURES IN WALLERIAN DEGENERATION .2. ELECTRON-MICROSCOPIC STUDY
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DOI:
10.1007/bf00691150
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发表时间:
1979-01-01
影响因子:
12.7
通讯作者:
ALLT, G
ALLT, G
中科院分区:
医学1区
文献类型:
--
作者:
GHABRIEL, MN;ALLT, G

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The EM of changes at Schmidt-Lanterman incisures in Wallerian degeneration has previously been described only briefly. The changes up to 36 h after nerve crush are chiefly peri-incisural. At 12 h and 24 h incisural dilatation consisted of an intraperiod line separation of peri-incisural myelin lamellae, which began among inner (adaxonal) lamellae extending later to outer (abaxonal) lamellae. The incisure itself showed little or no change. At 36 h, ovoid formation was apparent in most fibers. The sites of fiber cleavage to form ovoids occurred adjacent to incisures at the focal regions of myelin lamellae separation. Even within ovoids the incisures themselves remained intact at 36 h. The fine structural changes at incisures following nerve crush provide an understanding of the increased perceptibility of incisures by light microscopy during early Wallerian degeneration.