Evolutionary and Expression Analysis Provides Evidence for the Plant Glutamate-like Receptors Family is Involved in Woody Growth-related Function.
Evolutionary and Expression Analysis Provides Evidence for the Plant Glutamate-like Receptors Family is Involved in Woody Growth-related Function.
复制标题
进化和表达分析为植物谷氨酸样受体家族参与木本生长相关功能提供了证据
DOI：
10.1038/srep32013
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发表时间：
2016-08-24
影响因子：
4.6
通讯作者：
Wu J
中科院分区：
文献类型：
--
作者：
Chen J;Jing Y;Zhang X;Li L;Wang P;Zhang S;Zhou H;Wu J
谷氨酸样受体(GLRs)是一类高度保守的配体门控离子通道家族，参与多种生理和发育过程。在这里，我们研究了GLRin植物的进化模式。我们观察到串联复制在植物GLR基因家族的扩展中所占的比例最大。根据系统发育树，我们提出了一个新的亚科GLR4，该亚科在被子植物中广泛存在，而在十字花科中缺失。同时，由于GLR1和GLR2亚家族是潜在的姊妹分支，我们将它们合并为GLR1和GLR2亚家族。对植物GLR亚家族的比较分析表明，选择性作用力在真叶植物的茎中形成了具有不同功能偏好的GLR1&2谱系。此外，GLR1&2还形成了一个物种特有的高木扩展亚科，在高木树种富含形成层的部分和顶端分生组织中优先表达。总之，这些发现为植物GLR在整个植物时间尺度上的进化分析奠定了基础，并确定了操纵植物GLR木本生长行为的独特靶标。
Glutamate-like receptors (GLRs) is a highly conserved family of ligand-gated ion channels, which have been associated with various physiological and developmental processes. Here, we investigated the evolutionary pattern ofGLRsin plants. We observed that tandem duplications occupied the largest proportion of the plantGLRgene family expansion. Based on a phylogenetic tree, we suggested a new subfamily,GLR4, which is widespread in angiosperm but absence on Brassicales. Meanwhile, becauseGLR1andGLR2subfamilies were potential sister clades, we combined them into theGLR1&2subfamily. A comparative analysis of plantGLRsubfamilies revealed that selective forces shaped theGLR1&2repertoires in the stems of eudicotyledons with distinct functional preferences. Moreover,GLR1&2formed a species-specific highwoody-expanded subfamily, with preferential expression in the cambial-enriched and shoot apical meristem fractions of the highwood species. Together, these findings lay the foundation for evolutionary analysis of plantGLRsover the entire plant timescale and identified unique targets for manipulating the woody-growth behaviours of plant GLRs.