Pectoral Nerves I and II Blocks in Multimodal Analgesia for Breast Cancer Surgery A Randomized Clinical Trial

Pectoral Nerves I and II Blocks in Multimodal Analgesia for Breast Cancer Surgery A Randomized Clinical Trial
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DOI:
10.1097/aap.0000000000000163
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发表时间:
2015-01-01
影响因子:
5.1
通讯作者:
Abbas, Dina Nabil
Abbas, Dina Nabil
中科院分区:
医学2区
文献类型:
--
作者:
Bashandy, Ghada Mohammad Nabih;Abbas, Dina Nabil

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背景资料:I型和II型胸神经(佩奇)阻滞是阻滞胸肌、肋间臂、第三至第六肋间和胸长神经的新技术。它们可以在乳房手术期间和之后提供良好的镇痛。我们的研究旨在前瞻性地比较改良根治性乳腺切除术后使用全身麻醉和佩奇阻滞与单纯全身麻醉的镇痛质量。120例拟在全身麻醉下进行选择性单侧改良乳腺癌根治术的成年女性患者被随机分配接受全身麻醉加佩奇阻滞结果:佩奇组疼痛评分明显低于对照组,差异有统计学意义(P < 0. 05)。此外,佩奇组的术后吗啡消耗量在术后前12小时内低于对照组。此外,观察到佩奇组术中芬太尼消耗量低于对照组,且具有统计学显著性。在麻醉后监护室,与对照组相比,佩奇组的恶心和呕吐以及镇静评分较低。总体而言,麻醉后监护室和住院时间较短的佩奇组比在control group.Conclusions:联合佩奇我和II块是一个简单的,易于学习的技术,产生良好的镇痛根治性乳腺手术。
Background: The pectoral nerves (Pecs) block types I and II are novel techniques to block the pectoral, intercostobrachial, third to sixth intercostals, and the long thoracic nerves. They may provide good analgesia during and after breast surgery. Our study aimed to compare prospectively the quality of analgesia after modified radical mastectomy surgery using general anesthesia and Pecs blocks versus general anesthesia alone.Methods: One hundred twenty adult female patients scheduled for elective unilateral modified radical mastectomy under general anesthesia were randomly allocated to receive either general anesthesia plus Pecs block (Pecs group, n = 60) or general anesthesia alone (control group, n = 60).Results: Statistically significant lower visual analog scale pain scores were observed in the Pecs group than in the control group patients. Moreover, postoperative morphine consumption in the Pecs group was lower in the first 12 hours after surgery than in the control group. In addition, statistically significant lower intraoperative fentanyl consumption was observed in the Pecs group than in the control group. In the postanesthesia care unit, nausea and vomiting as well as sedation scores were lower in the Pecs group compared with the control group. Overall, postanesthesia care unit and hospital stays were shorter in the Pecs group than in the control group.Conclusions: The combined Pecs I and II block is a simple, easy-to-learn technique that produces good analgesia for radical breast surgery.