Fulminant hepatitis during self-medication with hydroalcoholic extract of green tea
Fulminant hepatitis during self-medication with hydroalcoholic extract of green tea
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DOI：
10.1097/00042737-200510000-00021
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发表时间：
2005-10-01
影响因子：
2.1
通讯作者：
Dao, T
中科院分区：
文献类型：
--
作者：
Gloro, R;Hourmand-Ollivier, I;Dao, T
尽管传统草药具有潜在的植物治疗作用和无毒的古老声誉，但传统草药以前曾涉及严重的不良事件。Exolise是绿色茶（Camellia sinensis）的80%乙醇干提取物，标准化为25%儿茶素，表示为表没食子儿茶素没食子酸酯，含有5-10%咖啡因。自1999年以来，它已在法国、比利时、西班牙和联合王国作为辅助疗法用于减肥方案。在各种研究中，迄今为止，绿色茶被认为具有潜在的肝脏保护特性。在这项研究中，我们报告了一例在使用Exolise自我用药期间发生暴发性肝炎，需要进行肝移植的病例。
Despite an ancient reputation for potential phytotherapeutic effects and innocuity, traditional herbal medicine has previously been implicated in severe adverse events. Exolise is an 80% ethanolic dry extract of green tea (Camellia sinensis) standardized at 25% catechins expressed as epigallocatechin gallate, containing 5-10% caffeine. It has been available in France, Belgium, Spain and the United Kingdom since 1999, as an adjuvant therapy for use in weight loss programmes. In various studies, green tea has to date been considered useful for its potential hepatic protective properties. In this study, we report a case of fulminant hepatitis during self-medication with Exolise, requiring liver transplantation.