The biomechanical characteristics of the bone-periodontal ligament-cementum complex.
The biomechanical characteristics of the bone-periodontal ligament-cementum complex.
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DOI：
10.1016/j.biomaterials.2010.05.024
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发表时间：
2010-09
期刊：
影响因子：
14
通讯作者：
Marshall, Grayson W.
中科院分区：
文献类型：
--
作者：
Ho, Sunita P.;Kurylo, Michael P.;Fong, Tiffany K.;Lee, Stephen S. J.;Wagner, Hanoch D.;Ryder, Mark I.;Marshall, Grayson W.
牙齿和牙槽骨之间的相对运动是由软硬组织界面促进的，包括牙周膜-骨(PDL-bone)和牙周膜-牙骨质(PDL-Cementum)。软硬组织界面负责附着，对骨-牙复合体的整体生物力学效率至关重要。本研究对人磨牙牙周膜-骨和牙骨质附着部位进行了研究，以确定牙周膜与骨和牙骨质的结构方向和结合情况。这些附着点从材料和力学组合的角度进行了表征，并与宏观尺度功能有关。高分辨率互补成像技术，包括原子力显微镜、扫描电子显微镜和微尺度X射线计算机断层扫描(Micro XCT™)，显示了两种截然不同的方向：环状和放射状。众所周知，在PDL间隙内，韧带的主要方向是放射状的(RAD-PDL)。有趣的是，在牙槽骨和牙骨质附近观察到PDL与RAD-PDL连续的圆周方向。用直径1~2μm的牙槽骨和牙骨质中的牙槽骨或Sharpey‘s纤维来识别牙周膜-牙周膜的整合。在化学和生物化学方面，邻近骨和牙骨质的CIR-PDL是由相对较高的碳和较低的钙确定的，包括定位于负责维持PDL-骨和PDL-牙骨质附着部位的软硬组织凝聚力、硬度和吸湿性的富含亮氨酸的小蛋白。综合的结构和化学性质提供了PDL-骨(PdL：10~50 Mpa；骨：0.2~9.6 Gpa)和PdL-牙骨质(Er范围：1.1~8.3 Gpa)的分级硬度特征，这与骨牙复合体的宏观功能有关。
The relative motion between the tooth and alveolar bone is facilitated by the soft-hard tissue interfaces which include periodontal ligament-bone (PDL-bone) and periodontal ligament-cementum (PDL-cementum). The soft-hard tissue interfaces are responsible for attachment and are critical to the overall biomechanical efficiency of the bone-tooth complex. In this study, the PDL-bone and PDL-cementum attachment sites in human molars were investigated to identify the structural orientation and integration of the PDL with bone and cementum. These attachment sites were characterized from a combined materials and mechanics perspective and were related to macro-scale function. High resolution complimentary imaging techniques including atomic force microscopy, scanning electron microscopy and micro-scale X-ray computed tomography (Micro XCT™) illustrated two distinct orientations of PDL; circumferential-PDL (cir-PDL) and radial-PDL (rad-PDL). Within the PDL-space, the primary orientation of the ligament was radial (rad-PDL) as is well known. Interestingly, circumferential orientation of PDL continuous with rad-PDL was observed adjacent to alveolar bone and cementum. The integration of the cir-PDL was identified by 1 to 2 μm diameter PDL-inserts or Sharpey’s fibers in alveolar bone and cementum. Chemically and biochemically the cir-PDL adjacent to bone and cementum was identified by relatively higher carbon and lower calcium including the localization of small leucine rich proteins responsible for maintaining soft-hard tissue cohesion, stiffness and hygroscopic nature of PDL-bone and PDL-cementum attachment sites. The combined structural and chemical properties provided graded stiffness characteristics of PDL-bone (Er range for PDL: 10 – 50 MPa; bone: 0.2 – 9.6 GPa) and PDL-cementum (Er range for cementum: 1.1 – 8.3 GPa), which was related to the macro-scale function of the bone-tooth complex.
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影响因子：
18.6
作者：
McCulloch, CAG;Lekic, P;McKee, MD
通讯作者：
McKee, MD
影响因子：
30.8
作者：
Kizawa, H;Kou, I;Ikegawa, S
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影响因子：
2.4
作者：
Benjamin, M;Toumi, H;Milz, S
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Milz, S
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3
作者：
Balooch, M.;Habelitz, S.;Marshall, G. W.
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Marshall, G. W.
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4.1
作者：
Kalamajski, Sebastian;Aspberg, Anders;Oldberg, Ake
通讯作者：
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