Two-Stage Revision for Prosthetic Joint Infection: Outcome and Role of Reimplantation Microbiology in 107 Cases

Two-Stage Revision for Prosthetic Joint Infection: Outcome and Role of Reimplantation Microbiology in 107 Cases
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DOI:
10.1016/j.arth.2013.12.027
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发表时间:
2014-06-01
影响因子:
3.5
通讯作者:
Syrjala, Hannu P. T.
Syrjala, Hannu P. T.
中科院分区:
医学2区
文献类型:
--
作者:
Puhto, Ari-Pekka;Puhto, Teija M.;Syrjala, Hannu P. T.

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二期翻修术广泛应用于人工关节感染的治疗。然而,两个阶段之间抗生素治疗的持续时间和再植入微生物学的作用存在争议。本研究的目的是评估二期翻修加抗生素治疗6周的再植入微生物学的结果和影响。我们回顾了2001年至2009年间接受二期翻修治疗的107例患者。治疗总成功率为94.4%。再植培养阳性5例(5.2%),仅1例失败。因此,我们在两个阶段的修订中,在两个阶段之间使用6周的抗生素疗程,取得了良好的效果。阳性的再植入培养似乎与较差的结果无关。(C)2014 Elsevier Inc.保留所有权利。
Two-stage revision is widely used for the treatment of prosthetic joint infections. However, the duration of antibiotic treatment between stages and role of reimplantation microbiology are controversial. The purpose of this study was to evaluate the outcome and influence of the reimplantation microbiology of two-staged revisions with 6 weeks of antibiotic treatment. We retrospectively reviewed 107 patients treated with two-stage revision between 2001 and 2009. The overall treatment success rate was 94.4%. The reimplantation cultures were positive in 5/97 (5.2%) cases, and only one of them failed. Therefore, we achieved excellent results with a 6-week course of antibiotics between stages in two-stage revision. Positive reimplantation cultures do not seem to be associated with worse outcomes. (C) 2014 Elsevier Inc. All rights reserved.