Phosphoinositides Break Microtubule Dynamics Symmetry in the Phragmoplast

Phosphoinositides Break Microtubule Dynamics Symmetry in the Phragmoplast
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磷酸肌醇破坏成膜体中的微管动力学对称性

DOI:
10.1016/j.tcb.2019.03.002
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发表时间:
2019
影响因子:
19
通讯作者:
Smertenko, Andrei
Smertenko, Andrei
中科院分区:
生物学1区
文献类型:
--
作者:
Smertenko, Andrei

文献摘要

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植物的细胞质分裂依赖于微管的不对称行为:在膜质先导区进行整体聚合,在膜体滞后区进行整体解聚。最近的研究结果表明,磷脂酰肌醇4-激酶β(PI4Kβ)在这种不对称性中起着重要作用,它促进了膜质形成滞后区的建立。
Plant cytokinesis rely on asymmetric behavior of microtubules: bulk polymerization at the phragmoplast leading zone and bulk depolymerization at the phragmoplast lagging zone. Recent findings demonstrate that phosphatidylinositol 4-kinase beta (PI4Kβ) plays an essential role in this asymmetry by facilitating the establishment of the phragmoplast lagging zone.