Imaging characteristics of initial chest computed tomography and clinical manifestations of patients with COVID-19 pneumonia
Imaging characteristics of initial chest computed tomography and clinical manifestations of patients with COVID-19 pneumonia
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DOI：
10.1007/s11604-020-00973-x
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发表时间：
2020-04-21
影响因子：
2.1
通讯作者：
Liang, Yi
中科院分区：
文献类型：
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作者：
Fan, Na;Fan, WenHui;Liang, Yi
目的探讨2019冠状病毒肺炎（COVID-19 pneumonia，COVID-19）患者的胸部CT影像学特点及临床表现。方法对2020年1月10日至2月12日确诊的150例新冠肺炎患者的临床及CT影像学特点进行分析。结果从症状出现到首次CT检查的时间为1 ~ 8d。双肺受累83例（55.33%），单肺受累67例（44.67%），其中左肺25例，右肺42例。49例肺内单发病灶33例（32.67%）多发性肺内病变68例（22.00%）弥漫性肺内病变67例（44.00%）胸膜下病变占44.67%，沿着支气管血管束病变24例占16.00%，两个部位病变59例占39.33%。磨玻璃结节< 10 mm者18例（12.00%），斑片状磨玻璃影伴或不伴实变者124例（82.67%），条索样病变8例（5.33%），胸腔积液6例（4.00%），淋巴结肿大2例（1.33%）。结论2019冠状病毒肺炎患者胸部首次CT表现以磨玻璃影为主，多累及单发病灶，多见于60岁以上患者< 35 years old and multiple sites and extensive area in patients >。病变部位以胸膜下及肺下叶后基底段多见，多表现为小叶间隔增厚，并伴有实变。
Purpose To investigate the chest CT imaging characteristics and clinical manifestations of patients with COVID-19 pneumonia. Methods This study included 150 patients with COVID-19 pneumonia diagnosed from January 10 to February 12, 2020 to analyze their clinical and CT imaging characteristics. Results The period between symptom onset and initial CT examination ranged from 1 to 8 days. There were 83 cases (55.33%) involving both lungs, 67 cases (44.67%) involving a single lung (left 25 cases and right 42 cases). There were 49 cases (32.67%) of single intrapulmonary lesion, 33 cases (22.00%) of multiple intrapulmonary lesions, 68 cases (44.00%) of diffused intrapulmonary lesions, 67 cases (44.67%) of subpleural lesions, 24 cases (16.00%) of lesions localizing along the bronchovascular bundles, and 59 cases (39.33%) with lesions in both locations. There were 18 cases (12.00%) exhibiting ground-glass nodules of < 10 mm, 124 cases (82.67%) of patchy ground-glass opacities with or without consolidation, 8 cases (5.33%) of cord-like lesions, 6 cases (4.00%) of pleural effusion, and 2 cases (1.33%) of enlarged lymph nodes. Conclusions The main manifestations of initial chest CT in COVID-19 pneumonia patients was ground-glass opacities, commonly involving single site in patients < 35 years old and multiple sites and extensive area in patients > 60 years old. The common lesion sites were the subpleural region and the posterior basal segments of the lower lobes, mostly showing thickening of the interlobular septum and mixed with consolidation.