Anti-tumor necrosis factor alpha monoclonal antibody (infliximab) for the treatment of Pyoderma gangrenosum associated with Crohn's disease.

Anti-tumor necrosis factor alpha monoclonal antibody (infliximab) for the treatment of Pyoderma gangrenosum associated with Crohn's disease.
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抗肿瘤坏死因子α单克隆抗体(英夫利昔单抗)用于治疗与克罗恩病相关的坏疽性脓皮病。

DOI:
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发表时间:
2003
期刊:
European journal of dermatology : EJD
影响因子:
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通讯作者:
F. Rossini
F. Rossini
中科院分区:
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文献类型:
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作者:
A. Zaccagna;A. Bertone;P. Puiatti;F. Picciotto;T. Sprujevnik;R. Santucci;F. Rossini

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在这里,我们报告一例坏疽性脓皮病(PG)与克罗恩病成功治疗英夫利昔单抗。这种药物在许多炎症性疾病中的疗效已经报道,但它在PG中的使用仅见于极少数病例。我们的研究证实,这种疗法是治疗PG的有效替代方案,PG通常对常规疗法无反应。
Here we report a case of Pyoderma gangrenosum (PG) associated with Crohn's disease successfully treated with infliximab. The efficacy of this drug in many inflammatory diseases has already been reported, but its use in PG has only been seen in very few cases. Our study confirms that this therapy is a valid alternative solution for treating PG, which is often unresponsive to conventional therapies.