Familial clustering of diabetic retinopathy in South Indian Type 2 diabetic patients
Familial clustering of diabetic retinopathy in South Indian Type 2 diabetic patients
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DOI：
10.1046/j.1464-5491.2002.00820.x
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发表时间：
2002-11-01
影响因子：
3.5
通讯作者：
Mohan, V
中科院分区：
文献类型：
--
作者：
Rema, M;Saravanan, G;Mohan, V
目的这项研究的目的是确定是否有家族聚集性的糖尿病视网膜病变南印度2型diabeticsubjects.Methods在1991年9月至1997年9月期间，322个家庭，至少有两个糖尿病的兄弟姐妹谁在我们的中心登记，并进行了视网膜检查被选中的研究。糖尿病病程最长的同胞被定义为先证者。结果糖尿病视网膜病变先证者兄弟姐妹中糖尿病视网膜病变的检出率为11.2%，糖尿病视网膜病变先证者兄弟姐妹中糖尿病视网膜病变的检出率为35.3%（P
Aim The aim of the study was to determine whether there is familial clustering of diabetic retinopathy among South Indian Type 2 diabetic subjects.Methods During the period September 1991 to September 1997, 322 families with at least two diabetic siblings who were registered at our centre and had undergone a retinal examination were selected for the study. The sibling with the longest duration of diabetes was defined as the proband. The prevalence of retinopathy was compared between the siblings of probands with and without retinopathy.Results Diabetic retinopathy was diagnosed in 11.2% of the siblings of the probands without diabetic retinopathy and in 35.3% of the siblings of the probands with diabetic retinopathy (P