Outcomes of malignant external otitis: survival vs mortality
Outcomes of malignant external otitis: survival vs mortality
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DOI：
10.3109/00016480902971247
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发表时间：
2010-01-01
影响因子：
1.4
通讯作者：
Tseng, Fen-Yu
中科院分区：
文献类型：
--
作者：
Chen, Chun-Nan;Chen, Yuh-Shyang;Tseng, Fen-Yu
结论。在恶性外耳炎(MEO)患者中，死亡率与年龄、性别、糖耐量、糖尿病(DM)病程、微生物、并存疾病或单个脑神经受累无关。严重并发症如颅底骨髓炎、颅内伸展、多颅神经受累等与死亡率相关。目标。分析在当今先进抗生素时代影响MEO患者生存的因素。病人和方法。收集了1993-2005年间诊断为MEO的患者。结果。共纳入26例患者，平均年龄63.7±10.2岁。所有患者都有糖尿病病史。脓液培养以铜绿假单胞菌(26.9%)、肺炎克雷伯菌(19.2%)和真菌(15.4%)为主。脑神经受累11例，其中面神经受累最多(38.46%)。并发症包括骨髓炎(11例)和颅内受累(3例)。12例行乳突切除术。共有五名患者死亡。
Conclusions. In patients with malignant external otitis (MEO), mortality was not related to age, sex, degree of glucose tolerance, duration of diabetes mellitus (DM), microorganism, comorbid disease, or involvement of a single cranial nerve. Severe complications such as skull base osteomyelitis, intracranial extension, and involvement of multiple cranial nerves were correlated with mortality. Objectives. To analyze the factors that affect the survival of patients with MEO in today's era of advanced antibiotics. Patients and methods. Patients with a diagnosis of MEO from 1993 to 2005 were collected. Results. A total 26 patients with a mean age of 63.7 +/- 10.2 years were included. All had a history of DM. Pseudomonas aeruginosa (26.9%), Klebsiella pneumoniae (19.2%), and fungus (15.4%) were most frequently found in pus cultures. Cranial nerves were involved in 11 patients: the facial nerve was most frequently (38.46%) involved. Complications such as osteomyelitis (11 patients) and intracranial involvement (3 patients) were noted in this series. Mastoidectomy was performed in 12 patients. A total of five patients died.