Generalization of reach adaptation and proprioceptive recalibration at different distances in the workspace
Generalization of reach adaptation and proprioceptive recalibration at different distances in the workspace
复制标题
DOI：
10.1007/s00221-014-4157-9
复制
发表时间：
2015-03-01
影响因子：
2
通讯作者：
Henriques, Denise Y. P.
中科院分区：
文献类型：
--
作者：
Mostafa, Ahmed A.;Kamran-Disfani, Rozbeh;Henriques, Denise Y. P.
研究表明，在工作空间的一个位置调整自己的伸展范围，可以推广到其他新的地点。这种视觉运动适应的泛化受新目标相对于训练位置的位置的影响，使得到达远离训练目标方向的新目标(即，类似于22.5度；Krakauer等人)。在J Neurosci 20：8916-8924,2000)与更接近训练方向的那些相比，显示出很少的概括性。然而，当到达相同方向但与训练目标不同距离的新目标时，泛化要广泛得多。在这项研究中，我们调查了手本体感觉(本体感觉重新校准)的变化，如REACH适应，是否概括到工作空间的不同距离。受试者通过旋转光标将他们的伸展范围调整到两个目标位置，距离起始位置13厘米。然后，我们将这些训练位置处的开环到达和感觉手部位置的变化与位于与训练目标相同方向但离原始位置更近(10厘米)或更远(15厘米)的新目标进行比较。我们发现，REACH适应推广到新的更近和更远的目标，程度与在训练目标距离下观察到的程度相同。相比之下，尽管在两个新距离上感觉到的手位置的变化是显著的，但对于新的-远距离位置，这种重新校准比训练位置要小。鉴于REACH适应在新的距离上完全泛化，而本体感觉重新校准在更远的距离上泛化程度较小，我们认为本体感觉重新校准可能独立于运动适应而发生，反之亦然。
Studies have shown that adapting one's reaches in one location in the workspace can generalize to other novel locations. Generalization of this visuomotor adaptation is influenced by the location of novel targets relative to the trained location such that reaches made to novel targets that are located far from the trained target direction (i.e., similar to 22.5A degrees; Krakauer et al. in J Neurosci 20:8916-8924, 2000) show very little generalization compared to those that are closer to the trained direction. However, generalization is much broader when reaching to novel targets in the same direction but at different distances from the trained target. In this study, we investigated whether changes in hand proprioception (proprioceptive recalibration), like reach adaptation, generalize to different distances of the workspace. Subjects adapted their reaches with a rotated cursor to two target locations at a distance of 13 cm from the home position. We then compared changes in open-loop reaches and felt hand position at these trained locations to novel targets located in the same direction as the trained targets but either at a closer (10 cm) or at a farther distance (15 cm) from the home position. We found reach adaptation generalized to novel closer and farther targets to the same extent as observed at the trained target distance. In contrast, while changes in felt hand position were significant across the two novel distances, this recalibration was smaller for the novel-far locations compared to the trained location. Given that reach adaptation completely generalized across the novel distances but proprioceptive recalibration generalized to a lesser extent for farther distances, we suggest that proprioceptive recalibration may arise independently of motor adaptation and vice versa.