Case Report.: Cutaneous cryptococcosis in a patient with systemic erythematous lupus
Case Report.: Cutaneous cryptococcosis in a patient with systemic erythematous lupus
复制标题
DOI：
10.1046/j.1439-0507.2001.00661.x
复制
发表时间：
2001-01-01
期刊：
影响因子：
4.9
通讯作者：
Mateo, A
中科院分区：
文献类型：
--
作者：
Ramos, L;López, C;Mateo, A
我们的真菌学参考中心诊断出首例与系统性红斑狼疮 (SLE) 相关的皮肤隐球菌病：一名 24 岁女性患者，诊断患有 SLE、肾病综合征、动脉高血压、IV 型肾小球肾炎肾功能不全以及右大腿和臀肌蜂窝组织炎。通过皮肤活检和血液培养分离新型隐球菌。通过乳胶凝集试验检测血清中的隐球菌抗原。由于患者对氟康唑静脉注射治疗无反应，因此给予两性霉素 B。她死于急性肾功能不全。
The first case of a cutaneous cryptococcosis associated with systemic erythematous lupus (SLE) diagnosed in our Mycology Reference Centre is presented: a 24-year-old female patient diagnosed with SLE, nephrotic syndrome, arterial hypertension, renal insufficiency due to glomerulonephritis type IV and cellulitis in the right thigh and gluteus. Cryptococcus neoformans was isolated by cutaneous biopsy and haemo-culture. Cryptococcal antigen was detected in serum by the latex agglutination test. As the patient did not respond to fluconazol intravenous treatment, amphotericin B administration was performed. She died of acute renal insufficiency.