Expansion of the Gene Ontology knowledgebase and resources.
Expansion of the Gene Ontology knowledgebase and resources.
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DOI：
10.1093/nar/gkw1108
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发表时间：
2017-01-04
影响因子：
14.9
通讯作者：
The Gene Ontology Consortium
中科院分区：
文献类型：
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作者：
The Gene Ontology Consortium
基因本体（GO）是一个关于基因和基因产物功能的可计算知识的综合资源。因此，它被生物医学研究界广泛用于组学和相关数据的分析。我们的持续重点是提高GO资源的质量和实用性，我们欢迎并鼓励生物学各个领域的研究人员的投入。在这次更新中，我们总结了GO知识库的当前内容，并提出了一些新的功能和改进，已经对本体，注释和工具。其中的亮点是：1）促进GO知识库的访问和应用的发展，2）对资源的扩展以及对生物系统和网络生物学因果模型描述的支持。要了解更多信息，请访问http://geneontology.org/。
The Gene Ontology (GO) is a comprehensive resource of computable knowledge regarding the functions of genes and gene products. As such, it is extensively used by the biomedical research community for the analysis of -omics and related data. Our continued focus is on improving the quality and utility of the GO resources, and we welcome and encourage input from researchers in all areas of biology. In this update, we summarize the current contents of the GO knowledgebase, and present several new features and improvements that have been made to the ontology, the annotations and the tools. Among the highlights are 1) developments that facilitate access to, and application of, the GO knowledgebase, and 2) extensions to the resource as well as increasing support for descriptions of causal models of biological systems and network biology. To learn more, visit http://geneontology.org/.