RETICULAR PSEUDODRUSEN - A RISK FACTOR IN AGE-RELATED MACULOPATHY

RETICULAR PSEUDODRUSEN - A RISK FACTOR IN AGE-RELATED MACULOPATHY
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DOI:
10.1097/00006982-199515030-00001
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发表时间:
1995-01-01
影响因子:
3.3
通讯作者:
SARKS, JP
SARKS, JP
中科院分区:
医学2区
文献类型:
--
作者:
ARNOLD, JJ;SARKS, SH;SARKS, JP

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背景:网状伪曲鲁森氏素指的是一个黄色的交织网络125 mu m至250 mu m宽,首先出现在上部外黄斑中,然后在圆周及以后延伸。与真正的drusen不同,它们不会在荧光素或吲哚氨基绿色的血管造影上荧光,并且最好在无红光或扫描激光眼镜的He-ne激光器中看到。在过去的三年中,这种临床特征。分子:所有与年龄相关的大肿瘤(ARM)的表现为66%在一只或两只眼睛中出现了或随后形成视网膜下新容器。外观归因于脉络膜的变化。结论:网状伪曲霉是易于识别的临床症状,并且可能是ARM中脉络膜新生血管形成的重要危险因素。
Background: Reticular pseudodrusen refer to a yellow interlacing network 125 mu m to 250 mu m wide appearing first in the superior outer macula and then extending circumferentially and beyond. Unlike true drusen, they do not fluoresce on fluorescein or indocyanine green angiography, and are best seen in red-free light or with the He-Ne laser of the scanning laser ophthalmoscope.Methods: One hundred patients have been seen in our retinal practice with this clinical feature in the past 3 years.Results: All had some manifestation of age-related maculopathy (ARM), and 66% had or subsequently developed subretinal new vessels in one or both eyes. The appearance is attributed to changes in the choroid.Conclusions: Reticular pseudodrusen are an easily recognizable clinical sign, and may be an important risk factor for choroidal neovascularization in ARM.