PANCREATIC SIGNAL INTENSITY ON T1-WEIGHTED FAT-SATURATION MR-IMAGES - CLINICAL CORRELATION
PANCREATIC SIGNAL INTENSITY ON T1-WEIGHTED FAT-SATURATION MR-IMAGES - CLINICAL CORRELATION
复制标题
DOI：
10.1002/jmri.1880050307
复制
发表时间：
1995-05-01
期刊：
影响因子：
--
通讯作者：
EHRLICH, SM
中科院分区：
文献类型：
--
作者：
WINSTON, CB;MITCHELL, DG;EHRLICH, SM
为了确定T1加权脂肪抑制（T1 FS）磁共振（MR）图像上胰腺信号强度（SI）低于肝脏信号强度是否可用于帮助预测胰腺疾病的存在，三名独立观察员在T1 FS图像上对89名患者的胰腺SI相对于肝脏和/或肾皮质进行分级。 结果与患者年龄和诊断相关。 47例胰腺正常的患者中，42例胰腺SI高于肝脏，其余与肝脏SI相等，无一例出现脂肪胰腺。 这5名患者的平均年龄为71岁，而胰腺比肝脏更强烈的患者的平均年龄为55岁（P = 0.02）。 在42例临床胰腺异常的患者中，只有8例胰腺SI高于肝脏。 SI高于肝脏的正常胰腺的阳性预测值为84%，SI小于或等于肝脏的异常胰腺的阳性预测值为88%，总体准确性为86%。 如果将60岁以下患者的正常胰腺SI定义为高于肝脏SI，60岁以上患者的正常胰腺SI定义为等于或高于肝脏SI，则正常SI的阳性预测值为76%，SI降低的阳性预测值为100%，总体准确度为83%。 胰腺SI低于肝脏SI与胰腺疾病高度相关，尤其是在年轻患者中。 胰腺SI轻度降低，与非病变肝脏相同，常见于无临床明显胰腺疾病的老年人。
To determine whether signal intensity (SI) of the pancreas that was less than that of liver on T1-weighted fat-suppressed (T1FS) magnetic resonance (MR) images could be used to help predict the presence of pancreatic disease, three blinded independent observers graded pancreatic SI relative to liver and/or renal cortex in 89 patients on T1FS images. Results were correlated with patient age and diagnosis. Among the 47 patients with a clinically normal pancreas, pancreatic SI was higher than that of liver in 42 and equal to that of liver in the rest, none of whom had evidence of fatty pancreas. These five patients had a mean age of 71 years, compared with 55 years for patients whose pancreas was more intense than liver (P = .02). Of the 42 patients with a clinically abnormal pancreas, only eight had pancreatic SI higher than that of liver. The positive predictive value for normal pancreas of an SI higher than that of liver was 84% and the positive predictive value for abnormal pancreas of an SI less than or equal to that of liver was 88%, with an overall accuracy of 86%. If normal pancreatic SI is defined as higher than that of liver for patients younger than 60 years and as equal to or higher than that of liver for patients older than 60 years, the positive predictive value of normal SI becomes 76%, the positive predictive value of decreased SI becomes 100%, and the overall accuracy becomes 83%. Pancreatic SI less than that of liver correlates highly with pancreatic disease, especially in younger patients. Mildly decreased pancreatic SI, equal to that of nondiseased liver, is common in older persons without clinically apparent pancreatic disease.