Genetic correlations between production and disease traits during first lactation in Holstein cows.
Genetic correlations between production and disease traits during first lactation in Holstein cows.
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荷斯坦奶牛第一次泌乳期间产量与疾病特征之间的遗传相关性。
DOI：
10.1017/s1751731113002048
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发表时间：
2014
期刊：
影响因子：
3.6
通讯作者：
M. Suzuki
中科院分区：
文献类型：
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作者：
K. Hagiya;T. Yamazaki;Y. Nagamine;K. Togashi;S. Yamaguchi;Y. Gotoh;T. Kawahara;Y. Masuda;M. Suzuki
本研究的目的是利用阈值线性随机回归试验日模型，估计荷斯坦奶牛首次泌乳期间产奶量、体细胞评分（SCS）、乳腺炎和爪腿疾病（CLDs）之间的遗传相关性。我们使用了牛奶、脂肪和蛋白质产量的每日记录；体细胞计数；以及2000年至2009年间在日本北海道产犊的46 771头初乳荷斯坦奶牛的乳腺炎和乳糜泻发病率。我们的多性状分析采用了二元记录（乳腺炎和CLDs）的阈值动物模型和产量性状的线性动物模型。对于负负性状和产量性状，均采用加性遗传效应对产乳天数的三次勒让德多项式进行随机回归。产量与疾病发病率之间的最高正遗传相关性（乳汁和乳腺炎为0.36，脂肪和乳腺炎为0.56，蛋白质和乳腺炎为0.24，乳汁和乳糜泻为0.32，脂肪和乳糜泻为0.44，蛋白质和乳糜泻为0.31）估计在产奶量高峰时（乳汁36至65天）。因此，关注早期泌乳量的选择可能会增加乳腺炎和乳糜泻的风险。SCS与乳腺炎或CLD发病率的正遗传相关性表明，选择在哺乳期早期减少SCS可以降低乳腺炎和CLD的发病率。
The aim of this study was to estimate genetic correlations between milk yield, somatic cell score (SCS), mastitis, and claw and leg disorders (CLDs) during first lactation in Holstein cows by using a threshold-linear random regression test-day model. We used daily records of milk, fat and protein yields; somatic cell count (SCC); and mastitis and CLD incidences from 46 771 first-lactation Holstein cows in Hokkaido, Japan, that calved between 2000 and 2009. A threshold animal model for binary records (mastitis and CLDs) and linear animal model for yield traits were applied in our multiple trait analysis. For both liabilities and yield traits, additive genetic effects were used as random regression on cubic Legendre polynomials of days on milk. The highest positive genetic correlations between yields and disease incidences (0.36 for milk and mastitis, 0.56 for fat and mastitis, 0.24 for protein and mastitis, 0.32 for milk and CLD, 0.44 for fat and CLD and 0.31 for protein and CLD) were estimated at about the time of peak milk yield (36 to 65 days in milk). Selection focused on early lactation yield may therefore increase the risk of mastitis and CLDs. The positive genetic correlations of SCS with mastitis or CLD incidence imply that selection to reduce SCS in the early stages of lactation would decrease the incidence of both mastitis and CLD.