HISTOLOGICAL EFFECTS OF DUCTAL LIGATION OF SALIVARY-GLANDS OF CAT

HISTOLOGICAL EFFECTS OF DUCTAL LIGATION OF SALIVARY-GLANDS OF CAT
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DOI:
10.1002/path.1711180407
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发表时间:
1976-01-01
影响因子:
7.3
通讯作者:
GARRETT, JR
GARRETT, JR
中科院分区:
医学1区
文献类型:
--
作者:
HARRISON, JD;GARRETT, JR

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在1天至1年的时间内,避开神经进行导管结扎后,显微镜下检查了42个下颌腺、32个舌下腺和31个腮腺。在最初的大小增加后,所有3个腺体都出现了全面萎缩。在腮腺中,反应是均匀的,并且有进行性萎缩,直到大多数腺泡极度萎缩。然而,在下颌下腺和舌下腺中,反应是非常不同的,尽管在一些腺体中,大多数腺泡极度萎缩,但在其他腺体中,萎缩程度要小得多,尽管结扎时间延长,但大多数剩余的腺泡表现或多或少与正常相似。这些结果与早期对导管结扎的实验研究结果相反,但与对人类唾液腺行为的观察结果相似。
Forty-two submandibular, 32 sublingual and 31 parotid glands were examined microscopically after ductal ligation avoiding the nerves for periods from 1 day-1 yr. After an initial increase in size, there was over-all atrophy in all 3 glands. In the parotid gland the response was uniform and there was progressive atrophy until most of the acini were extremely atrophic. However, in the submandibular and sublingual glands the response was very variable, and although in some glands most of the acini were extremely atrophic, in other glands there was far less atrophy and most of the remaining acini appeared more or less similar to normal despite prolonged ligation. These results contrast with those of earlier experimental studies on ductal ligation, but have similarities with observations on the behavior of human salivary glands.