MOLECULAR DIAGNOSIS OF SEPSIS: NEW ASPECTS AND RECENT DEVELOPMENTS

MOLECULAR DIAGNOSIS OF SEPSIS: NEW ASPECTS AND RECENT DEVELOPMENTS
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DOI:
10.1556/eujmi.4.2014.1.1
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发表时间:
2014-03-01
影响因子:
2.2
通讯作者:
Kost, G.
Kost, G.
中科院分区:
其他
文献类型:
--
作者:
Liesenfeld, O.;Lehman, L.;Kost, G.

文献摘要

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通过缩短病原体鉴定的时间并允许检测血液培养遗漏的生物体,新的分子方法可能为脓毒症患者的管理提供临床益处。虽然最近发表了许多关于败血症诊断的评论,但我们在这里介绍了最新的新进展,包括多重PCR、质谱和阵列技术。我们专注于那些商业上可用的技术,并已进行临床研究和出版。
By shortening the time to pathogen identification and allowing for detection of organisms missed by blood culture, new molecular methods may provide clinical benefits for the management of patients with sepsis. While a number of reviews on the diagnosis of sepsis have recently been published we here present up-to-date new developments including multiplex PCR, mass spectrometry and array techniques. We focus on those techniques that are commercially available and for which clinical studies have been performed and published.