Maternal risk factors associated with increased dioxin concentrations in breast milk in a hot spot of dioxin contamination in Vietnam
Maternal risk factors associated with increased dioxin concentrations in breast milk in a hot spot of dioxin contamination in Vietnam
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DOI：
10.1038/jes.2013.73
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发表时间：
2014-09-01
影响因子：
4.5
通讯作者：
Nishijo, Hisao
中科院分区：
文献类型：
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作者：
Nguyen Thi Nguyet Anh;Nishijo, Muneko;Nishijo, Hisao
本研究旨在确定越南二恶英暴露热点地区母乳喂养妇女的母乳中二恶英暴露的决定因素。从140名分娩后1个月的母亲中收集母乳。调查的危险因素包括居住时间、饮用井水和食用动物性食物的频率。采用聚类分析确定鱼和肉部分、鱼品种和蛋品种的膳食模式。居住地、年龄和胎次明显与二恶英水平升高有关。饮用井水和食用海蟹和虾与母乳中呋喃含量较高有关。鹌鹑蛋的食用似乎也与该地区某些二恶英异构体水平的增加有关。一些不吃肉或吃肉少于鱼的母亲，以及食用淡水鱼多于海鱼的母亲，其母乳中的二恶英含量较低。然而，水的种类和母亲的饮食习惯只是母乳中二恶英含量增加的部分原因；居住时间长短是与母亲二恶英身体负担增加相关的最重要风险因素。
This study looked to identify determinants of exposure to dioxin in breast milk from breast-feeding women in a hot spot of dioxin exposure in Vietnam. Breast milk was collected from 140 mothers 1 month after delivery. The risk factors investigated included length of residency, drinking of well water and the frequency of animal food consumption. Cluster analysis was performed to identify dietary patterns of fish and meat portions, fish variety and egg variety. Residency, age and parity were clearly associated with increased dioxin levels. Drinking well water and the consumption of marine crab and shrimps were related to higher levels of furans in breast milk. The consumption of quail eggs also appeared to be associated with increased levels of some dioxin isomers in this area. Some mothers who ate no or less meat than fish and mothers who consumed more freshwater fish than marine fish had lower levels of dioxins in their breast milk. However, the type of water and the eating habits of mothers contributed only partly to the increased dioxin levels in their breast milk; the length of residency was the most important risk factor associated with increased dioxin body burdens of mothers.