Testing against a high-dimensional alternative in the generalized linear model: asymptotic type I error control

Testing against a high-dimensional alternative in the generalized linear model: asymptotic type I error control
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DOI:
10.1093/biomet/asr016
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发表时间:
2011-06-01
期刊:
影响因子:
2.7
通讯作者:
Finos, Livio
Finos, Livio
中科院分区:
数学2区
文献类型:
--
作者:
Goeman, Jelle J.;Van Houwelingen, Hans C.;Finos, Livio

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Testing a low-dimensional null hypothesis against a high-dimensional alternative in a generalized linear model may lead to a test statistic that is a quadratic form in the residuals under the null model. Using asymptotic arguments, we show that the distribution of such a test statistic can be approximated by a ratio of quadratic forms in normal variables, for which algorithms are readily available. For generalized linear models, the asymptotic distribution shows good control of type I error for moderate to small samples, even when the number of covariates in the model far exceeds the sample size.