Food insecurity and cognitive function in Puerto Rican adults
Food insecurity and cognitive function in Puerto Rican adults
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DOI：
10.3945/ajcn.2008.26941
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发表时间：
2009-04-01
影响因子：
7.1
通讯作者：
Tucker, Katherine L.
中科院分区：
文献类型：
--
作者：
Gao, Xiang;Scott, Tammy;Tucker, Katherine L.
背景：粮食不安全与营养不足和各种不利的健康后果有关。目的：我们调查了居住在马萨诸塞州的1358名45-75岁波多黎各人的食物不安全的患病率与认知功能表现的关系。设计：用美国家庭食物安全量表评估食物安全。认知功能的测量包括7项测试：简易智力状态检查(MMSE)、单词列表学习(词汇记忆)、数字广度(注意力)、时钟绘制和图形复制(视觉空间能力)、Stroop和语言流利性测试(流利性执行功能)。结果：过去12个月内食物不安全的总患病率为12.1%；6.1%的受试者报告食物安全性非常低。根据MMSE评分，食物不安全与全球认知表现呈负相关。在对年龄、吸烟、教育程度、贫困状况、收入、文化适应、血浆同型半胱氨酸、酒精、糖尿病和高血压进行调整后，食物安全度极低的参与者与食物安全者进行比较，调整后的MMSE得分差异为-0.9(95%CI：-1.60，-0.19；趋势0.003)。食物不安全感与词表学习、百分比保持、字母流利性和数字广度倒退测试得分较低显著相关。结论：食物安全感在研究对象中普遍存在，并与认知能力低下有关。进一步的研究，无论是观察性的还是实验性的，都有必要澄清这种联系中因果关系的方向。AM J Clin Nutr 2009；89：1197-203。
Background: Food insecurity is associated with nutrient inadequacy and a variety of unfavorable health outcomes. However, little is known about whether food security is associated with lower cognitive function in the elderly.Objective: We investigated the prevalence of food insecurity in a representative sample of 1358 Puerto Ricans aged 45-75 y living in Massachusetts in relation to cognitive function performances.Design: Food security was assessed with the US Household Food Security Scale. Cognitive function was measured to capture general cognition with a battery of 7 tests: Mini-Mental State Examination (MMSE), word list learning (verbal memory), digit span (attention), clock drawing and figure copying (visual-spatial ability), and Stroop and verbal fluency tests (fluency executive functioning).Results: The overall prevalence of food insecurity during the past 12 mo was 12.1%; 6.1% of the subjects reported very low food security. Food insecurity was inversely associated with global cognitive performance, as assessed by the MMSE score. The adjusted difference in the MMSE score was -0.90 (95% CI: -1.6, -0.19; P for trend 0.003) for a comparison of participants with very low food security with those who were food secure, after adjustment for age, smoking, education, poverty status, income, acculturation, plasma homocysteine, alcohol, diabetes, and hypertension. Food insecurity was significantly associated with lower scores for word-list learning, percentage retention, letter fluency, and digit span backward tests.Conclusions: Very low food security was prevalent among the study subjects and was associated with lower cognitive performance. Further studies, both observational and experimental, are warranted to clarify the direction of causality in this association. Am J Clin Nutr 2009; 89: 1197 -203.