CODON FREQUENCIES IN 119 INDIVIDUAL GENES CONFIRM CONSISTENT CHOICES OF DEGENERATE BASES ACCORDING TO GENOME TYPE
CODON FREQUENCIES IN 119 INDIVIDUAL GENES CONFIRM CONSISTENT CHOICES OF DEGENERATE BASES ACCORDING TO GENOME TYPE
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DOI：
10.1093/nar/8.9.1893
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发表时间：
1980-01-01
影响因子：
14.9
通讯作者：
GOUY, M
中科院分区：
文献类型：
--
作者：
GRANTHAM, R;GAUTIER, C;GOUY, M
我们之前的图2(1)的糟糕打印已被更正。文中还给出了刚发表的mRNA序列中密码子的用法。基于61个密码子使用的所有信使核糖核酸的同时比较，进行了新的对应分析。这一分析强化了我们的主张，即基因组或基因组类型中的大多数基因具有相同的编码策略；即，它们在同义密码子或退化碱基之间表现出类似的选择。与对编码的氨基酸的频率变化的分析一样，揭示了完全不同的模式。
The poor printing of our previous Figure 2 (1) is corrected. Codon usage in mRNA sequences just published is also given. A new correspondence analysis is done, based on simultaneous comparison in all mRNA of use of the 61 codons. This analysis reinforces our claim that most genes in a genome, or genome type, have the same coding strategy; that is, they show similar choices among synonymous codons, or among degenerate bases (2). Like analysis on frequency variation in the amino acids coded reveals an entirely different pattern.