Investigating the Genomic Distribution of Phylogenetic Signal with CloudForest
Investigating the Genomic Distribution of Phylogenetic Signal with CloudForest
复制标题
使用 CloudForest 研究系统发育信号的基因组分布
DOI:
10.1145/3437359.3465605
复制
发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Wilgenbusch, James C.
中科院分区:
文献类型:
--
作者:
Wagner, Reid;Toups, Benjamin S.;Deng, Zhifeng;Gallivan, Kyle A.;Brown, Jeremy M.;Wilgenbusch, James C.
A central focus of evolutionary biology is inferring the historical relationships among species and using this context to learn about how evolution has shaped diverse organisms. These historical relationships are represented by phylogenetic trees, and the methods used to infer these trees have been an active area of research for several decades. Despite this attention, phylogenetic workflows have changed little, even though extraordinary advances have occurred in the scale and pace at which genomic data have been collected in the past 20 years. Modern phylogenomic datasets have also raised fascinating new questions. Why do different parts of a genome often support different relationships among species? How are these different signals distributed across chromosomes? We developed a new computational framework, CloudForest, to tackle such questions. CloudForest is flexible, efficient, and tightly integrates a diverse set of tools. Here, we briefly describe the architecture of CloudForest, including the advantages it provides, and use it to investigate the distribution of phylogenetic signal along the entire X chromosome of 24 cat (Felidae) species.
影响因子:
6.5
作者:
James C. Wilgenbusch;Kevin de Queiroz
通讯作者:
Kevin de Queiroz
影响因子:
10.7
作者:
Li, Gang;Figueiro, Henrique;Murphy, William J.
通讯作者:
Murphy, William J.
影响因子:
3
作者:
James C. Wilgenbusch;Wen Huang;K. Gallivan
通讯作者:
K. Gallivan