SMALL HEPATOCELLULAR-CARCINOMA - DIAGNOSIS WITH US ANGIOGRAPHY WITH INTRAARTERIAL CO-2 MICROBUBBLES
SMALL HEPATOCELLULAR-CARCINOMA - DIAGNOSIS WITH US ANGIOGRAPHY WITH INTRAARTERIAL CO-2 MICROBUBBLES
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DOI：
10.1148/radiology.182.1.1309216
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发表时间：
1992-01-01
期刊：
影响因子：
19.7
通讯作者：
TODO, A
中科院分区：
文献类型：
--
作者：
KUDO, M;TOMITA, S;TODO, A
对95例103例经组织学证实的直径小于3cm的肝细胞癌（HCC）进行了动脉内CO2微泡超声（US）血管造影增强。 将超声血管造影对富血供HCC的检出率与常规血管造影、数字减影血管造影（DSA）和碘油动脉内注射后计算机断层扫描（CT）的检出率进行比较。 超声血管造影检测富血供HCC的敏感性为86%（89/103），而常规血管造影检测的敏感性为63%（44/70），DSA检测的敏感性为70%（23/33），碘油CT检测的敏感性为82%（75/91）。 超声血管造影显示了小的多血管HCC，特别是直径小于1 cm的HCC，有助于明确血管造影无法检测到的HCC中的血管分布。 超声血管造影的结果有助于肝细胞癌治疗策略的选择，如经动脉治疗、经皮无水乙醇注射治疗或切除。
Ultrasonographic (US) angiography enhanced with intraarterial CO2 microbubbles, a contrast material used in US imaging, was performed of 103 histologically proved hepatocellular carcinomas (HCCs) smaller than 3 cm in diameter in 95 patients. The detection rate for hypervascular HCC with US angiography was compared with the rate of detection with conventional angiography, digital subtraction angiography (DSA), and computed tomography (CT) after intraarterial injection of iodized oil. Sensitivity in detection of hypervascular HCCs with US angiography was 86% (89 of 103 HCCs), compared with 63% (44 of 70 HCCs) detected with conventional angiography, 70% (23 of 33 HCCs) with DSA, and 82% (75 of 91 HCCs) with CT with iodized oil. US angiography depicted small hypervascular HCCs, especially those less than 1 cm in diameter, and helped clarify vascularity as isovascular or hypovascular in angiographically undetectable HCCs. Findings at US angiography assisted the choice of a therapeutic strategy for treatment of HCC, such as transarterial therapy, percutaneous ethanol injection therapy, or resection.