Household Air Pollution and Acute Lower Respiratory Infections in Adults: A Systematic Review.
Household Air Pollution and Acute Lower Respiratory Infections in Adults: A Systematic Review.
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DOI：
10.1371/journal.pone.0167656
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Mortimer K
中科院分区：
文献类型：
--
作者：
Jary H;Simpson H;Havens D;Manda G;Pope D;Bruce N;Mortimer K
固体燃料燃烧造成的家庭空气污染每年造成400多万人死亡，其中包括50万儿童急性下呼吸道感染。虽然在生物学上是合理的，但尚不清楚家庭空气污染是否也与成人急性下呼吸道感染有关。我们系统地回顾了有关家庭空气污染和成人急性下呼吸道感染的文献，以确定知识差距和研究机会。检索了10个书目数据库，以确定家庭空气污染和成人急性下呼吸道感染的研究。使用标准化表格从合格研究中提取数据。从4617个标题，513个摘要和72个全文的文章进行了审查。8项研究符合纳入标准，其中2项发现急性下呼吸道感染的校正风险显著增加，2项确定了单变量相关性，4项未发现显著相关性。研究质量普遍有限。异质结的方法和结果排除了荟萃分析。对文献的系统性回顾发现，家庭空气污染与成人急性下呼吸道感染风险之间存在关联的证据有限。需要进行进一步的研究，仔细界定暴露和结果措施，以完成家庭空气污染对成年人造成的风险简介。CRD42015028042。
Household air pollution from solid fuel burning kills over 4 million people every year including half a million children from acute lower respiratory infections. Although biologically plausible, it is not clear whether household air pollution is also associated with acute lower respiratory infections in adults. We systematically reviewed the literature on household air pollution and acute lower respiratory infection in adults to identify knowledge gaps and research opportunities. Ten bibliographic databases were searched to identify studies of household air pollution and adult acute lower respiratory infection. Data were extracted from eligible studies using standardised forms. From 4617 titles, 513 abstracts and 72 full-text articles were reviewed. Eight studies met the inclusion criteria of which 2 found a significant adjusted increased risk of acute lower respiratory infection, 2 identified a univariate association whilst 4 found no significant association. Study quality was generally limited. Heterogeneity in methods and findings precluded meta-analysis. A systematic review of the literature found limited evidence for an association between household air pollution and risk of acute lower respiratory infection in adults. Additional research, with carefully defined exposure and outcome measures, is required to complete the risk profile caused by household air pollution in adults. CRD42015028042.