Effects of a Home-Based Intervention on HIV Prevention Health Behaviors in Pregnant/Postpartum Kenyan Women: Estimating Moderating Effects of Depressive Symptoms.
Effects of a Home-Based Intervention on HIV Prevention Health Behaviors in Pregnant/Postpartum Kenyan Women: Estimating Moderating Effects of Depressive Symptoms.
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DOI：
10.1007/s10461-020-03046-2
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发表时间：
2021-04
影响因子：
4.4
通讯作者：
Turan JM
中科院分区：
文献类型：
--
作者：
Anderson JL;Li P;Bukusi EA;Darbes LA;Hatcher AM;Helova A;Kwena ZA;Musoke PL;Owino G;Oyaro P;Rogers AJG;Turan JM
我们利用患者健康问卷 8 (PHQ-8) 评估了母亲抑郁症状对肯尼亚米戈里县妇女艾滋病毒预防行为的影响。 ≥18 岁、胎龄 <37 周的孕妇被随机分配到标准护理组或 3 次家访（2 次怀孕期间，1 次产后），以促进夫妇 HIV 检测和咨询 (CHTC) 以及 HIV 预防。在 105 名女性参与者中，37 名（35.24%）报告有抑郁症状，50 名（47.62%）艾滋病毒呈阳性。三个具有稳健方差的泊松回归（单变量、多变量和具有抑郁症状/研究组相互作用的多变量）针对三种结果进行建模：CHTC、婴儿 HIV 检测、产后寻求健康。在具有交互作用的多变量分析中，观察到抑郁症状与个人健康寻求之间的交互作用呈缓和趋势（p 值=0.067）。与标准护理参与者相比，PHQ-8 得分≤9（n=68）并参加家访的女性参与个人健康寻求的可能性高出 1.76 倍（ARR 1.76，95% CI 1.17-2.66）。
We estimated effects of maternal depressive symptoms, utilizing the Patient Health Questionnaire-8 (PHQ-8), on women’s HIV prevention behaviors in Migori County, Kenya. Pregnant women ≥18 years old, with gestational age of <37 weeks, were randomized into standard care or three home visits (2 during pregnancy, 1 postpartum) promoting couples HIV testing and counseling (CHTC) and HIV prevention. Of 105 female participants, 37 (35.24%) reported depressive symptoms and 50 (47.62%) were HIV-positive. Three Poisson regressions with robust variance (univariable, multivariable, and multivariable with depressive symptoms/study arm interaction) were modeled for three outcomes: CHTC, infant HIV testing, health-seeking postpartum. In multivariable analysis with interaction, a moderating trend for the interaction between depressive symptoms and individual health-seeking was observed (p-value=0.067). Women scoring ≤9 (n=68) on the PHQ-8 and participating in home visits were 1.76 times more likely to participate in individual health-seeking compared to participants in standard care (ARR 1.76, 95% CI 1.17–2.66).
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影响因子：
3.7
作者：
Colvin CJ;Konopka S;Chalker JC;Jonas E;Albertini J;Amzel A;Fogg K
通讯作者：
Fogg K
影响因子：
3.1
作者：
Deressa W;Seme A;Asefa A;Teshome G;Enqusellassie F
通讯作者：
Enqusellassie F
影响因子：
3.7
作者：
Hodgson I;Plummer ML;Konopka SN;Colvin CJ;Jonas E;Albertini J;Amzel A;Fogg KP
通讯作者：
Fogg KP
影响因子：
1.6
作者：
Bello, Fatimah Oluwakemi;Musoke, Pamela;Turan, Janet M.
通讯作者：
Turan, Janet M.
影响因子：
4.5
作者：
Becker, Stan;Taulo, Frank O.;Tsui, Amy
通讯作者：
Tsui, Amy