Health-related Quality of Life across the anxiety disorders: Findings from a sample of primary care patients

Health-related Quality of Life across the anxiety disorders: Findings from a sample of primary care patients
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DOI:
10.1016/j.janxdis.2010.03.015
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发表时间:
2010-08-01
影响因子:
10.3
通讯作者:
Keller, Martin B.
Keller, Martin B.
中科院分区:
医学2区
文献类型:
--
作者:
Beard, Courtney;Weisberg, Risa B.;Keller, Martin B.

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先前的研究没有比较所有DSM-IV焦虑症和合并症的健康相关生活质量(HR-QoL)。我们比较了每种焦虑症对HR-QoL的影响,控制了人口统计学变量、医疗条件和共病轴I障碍。数据来自初级保健焦虑项目(PCAP),这是一项对539名初级保健患者的焦虑障碍进行的自然的纵向研究。与一般人群相比,每一种焦虑症都与自我报告的更差的身体和精神功能有关。虽然所有焦虑症都是HR-QoL特定领域的单变量预测因子,但只有创伤后应激障碍(PTSD)和共病性抑郁症(MDD)的存在在自我报告和访谈测量中都能独特地预测更差的功能。目前的研究扩展了先前的研究,表明不同的焦虑障碍和合并症可能与HR-QoL特定领域的损害有关。(C) 2010 Elsevier Ltd.版权所有。
Previous studies have not compared Health-related Quality of Life (HR-QoL) across all DSM-IV anxiety disorders and comorbid conditions. We compared the effects of each anxiety disorder on HR-QoL, controlling for demographic variables, medical conditions, and comorbid Axis I disorders. Data are obtained from the Primary Care Anxiety Project (PCAP), a naturalistic, longitudinal study of anxiety disorders in 539 primary care patients. Each of the anxiety disorders was associated with worse self-reported physical and mental functioning compared to general population means. While all of the anxiety disorders were univariate predictors of specific domains of HR-QoL, only presence of Post-traumatic Stress Disorder (PTSD) and comorbid Depressive Disorder (MDD) uniquely predicted worse functioning on both self-report and interview measures. The current study extends previous research by showing that different anxiety disorders and comorbid conditions may be associated with impairment in specific domains of HR-QoL. (C) 2010 Elsevier Ltd. All rights reserved.