Clinicopathologic study of resected, peripheral, small-sized, non-small cell lung cancer tumors of 2 cm or less in diameter: Pleural invasion and increase of serum carcinoembryonic antigen level as predictors of nodal involvement
Clinicopathologic study of resected, peripheral, small-sized, non-small cell lung cancer tumors of 2 cm or less in diameter: Pleural invasion and increase of serum carcinoembryonic antigen level as predictors of nodal involvement
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DOI：
10.1016/j.jtcvs.2005.12.035
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发表时间：
2006-05-01
影响因子：
6
通讯作者：
Okumura, M
中科院分区：
文献类型：
--
作者：
Inoue, M;Minami, M;Okumura, M
目的：随着计算机断层扫描技术的发展，外科手术治疗小肺癌的数量不断增加。我们试图找出周围，小尺寸，非小细胞肺癌的临床病理特征，以显示部分切除或segmentectomy.Methods的局限性：回顾性分析143例患者进行了完整的切除周围非小细胞肺癌直径为2厘米或更小。在接受肺叶切除加淋巴结清扫的患者中，也评估了淋巴结受累与其他临床因素之间的关系。肿瘤小于等于1.5 cm的患者5年生存率为100%，腺癌组织学患者的生存率明显高于非腺癌组织学患者（P= 0.03）。无淋巴结转移者5年生存率为91.6%，有淋巴结转移者5年生存率为62.5%（P
Objective: The number of surgical interventions for small-sized lung cancer has increased with the development of computed tomography. We attempted to identify clinicopathologic characteristics of peripheral, small-sized, non-small cell lung cancer to show the limitation of partial resection or segmentectomy.Methods: A retrospective analysis of 143 patients who underwent a complete resection for a peripheral non-small cell lung cancer of 2 cm or less in diameter was performed. The relationships between nodal involvement and other clinical factors were also assessed in patients who underwent a lobectomy plus node dissection.Results: The overall 5-year survival rate was 88.1%. The 5-year survival rate was 100% for patients with a tumor of 1.5 cm or less. Survival for patients with adenocarcinoma histology was significantly better than for those with nonadenocarcinoma histology (P=.03). The 5-year survival rate for patients without lymph node metastases was 91.6%, whereas it was 62.5% for those with nodal involvement (P