Supramolecular nanosubstrate-mediated delivery for reprogramming and transdifferentiation of mammalian cells.
Supramolecular nanosubstrate-mediated delivery for reprogramming and transdifferentiation of mammalian cells.
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DOI：
10.1002/smll.201402602
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发表时间：
2015-06-03
期刊：
影响因子：
--
通讯作者：
Tseng HR
中科院分区：
文献类型：
--
作者：
Hou S;Choi JS;Chen KJ;Zhang Y;Peng J;Garcia MA;Yu JH;Thakore-Shah K;Ro T;Chen JF;Peyda P;Fan G;Pyle AD;Wang H;Tseng HR
“Supramolecular NanoSubstrate Mediated Delivery (SNSMD)” leverages the power of molecular self-assembly and a nanostructured substrate platform for low toxic, no integrative, and highly efficient multiple delivery of biological factor-encapsulated in a nano-vector. In this study, human fibroblasts were successfully reprogrammed into induced pluripotent stems and transdifferentiated into induced neuronal like cell using the SNSMD platform.
