DIFFERENT TYPES OF SLOWLY CONDUCTING AFFERENT UNITS IN CAT SKELETAL-MUSCLE AND TENDON
DIFFERENT TYPES OF SLOWLY CONDUCTING AFFERENT UNITS IN CAT SKELETAL-MUSCLE AND TENDON
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DOI：
10.1113/jphysiol.1985.sp015718
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发表时间：
1985-01-01
影响因子：
5.5
通讯作者：
MEYER, H
中科院分区：
文献类型：
--
作者：
MENSE, S;MEYER, H
在氯醛糖麻醉猫，脉冲活动的单一传入单位进行小于30 m s-1，并在小腿三头肌或跟骨肌腱的感受野，记录从细细丝的背根[腰] L7和[SCARAL] S1。接受领域的单位进行了测试，各种分级的自然刺激（局部压力，拉伸，收缩，温度变化）。此外，痛觉剂缓激肽被注射到感受野，但受体对这种物质的敏感性不用于分类目的。用对无害的自然刺激的最强反应作为表征给定结局的标准，可以区分四种类型的受体：对无害形式的刺激没有反应，需要伤害性刺激的伤害感受器。（组织威胁）刺激被明显激活：低阈值压力敏感受体响应组织的无害压痕，但对拉伸和收缩相对不敏感;收缩敏感受体在中等力和无害拉伸的主动收缩期间达到高放电频率，但对局部压力刺激相对不敏感;热敏受体对温度的微小变化反应强烈，而对无害机械刺激无反应。不同类型的受体可能参与中枢神经功能（伤害感受，mechanoreception，ergoseception，体温调节）进行了讨论。
In chloralose-anesthetized cats, the impulse activity of single afferent units conducting at less than 30 m s-1 and having receptive fields in the triceps surae muscle or the calcaneal tendon, was recorded from thin filaments of the dorsal roots [lumbar] L7 and [scaral] S1. The receptive fields of the units were tested with a variety of graded natural stimuli (local pressure, stretch, contractions, temperature changes). In addition, the algesic agent bradykinin was injected into the receptive fields, but the sensitivity of the receptors to this substance was not used for classification purposes. Four types of receptors could be distinguished using the strongest response to innocuous natural stimulation as the criterion for characterizing a given ending: nociceptors showing no response to innocuous forms of stimulation and requiring noxious (tissue-threatening) stimuli to be clearly activated: low-threshold pressure-sensitive receptors responding to innocuous indentation of the tissue but being relatively insensitive to stretch and contractions; contraction-sensitive receptors reaching high discharge frequencies during active contractions of moderate force and innocuous stretch, but being relatively insensitive to local pressure stimulation; thermosensitive receptors responding strongly to small changes in temperature without reacting to innocuous mechanical stimulation. The possible involvement of the different receptor types in central nervous function (nociception, mechanoreception, ergoreception, thermoregulation) is discussed.