Prevalence of neurocysticercosis among people with epilepsy in rural areas of Burkina Faso.
Prevalence of neurocysticercosis among people with epilepsy in rural areas of Burkina Faso.
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DOI：
10.1111/j.1528-1167.2012.03687.x
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发表时间：
2012-12
期刊：
影响因子：
5.6
通讯作者：
Cissé R
中科院分区：
文献类型：
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作者：
Millogo A;Nitiéma P;Carabin H;Boncoeur-Martel MP;Rajshekhar V;Tarnagda Z;Praet N;Dorny P;Cowan L;Ganaba R;Hounton S;Preux PM;Cissé R
估计布基纳法索三个村庄神经囊虫病（NCC）相关癫痫的终生患病率和NCC在癫痫患者中的比例。三个村庄被选为代表三种养猪方法：1）Batondo，猪被留在那里漫游; 2）Pabré，猪大多被拴在一起或关在围栏里; 3）Nyonyogo，大多数居民是穆斯林，很少养猪。在Batondo和Nyonyogo，所有租让地（几个家庭组成的小组）都包括在内。Pabré的特许经营权有一半是随机挑选的。选定的特许经营区的所有住户都包括在内，每户随机挑选一人进行癫痫筛查和囊虫病血清学检测。还检查了自我报告的癫痫病例，并将确诊病例纳入分析，而不是估计NCC相关癫痫患病率。癫痫被定义为曾经有过一次以上的无端癫痫发作。经医学证实的癫痫病例在注射造影剂前后进行了脑部计算机断层扫描（CT）。NCC的诊断是使用标准的修改。随机抽取的888名村民中有39名（4.4%）和35名自我报告的癫痫发作病例中有33名（94.3%）被医学检查证实患有癫痫。在接受CT扫描的68名癫痫患者中，20名患者被诊断为明确或可能的NCC，Batondo的比例为46.9%（95%CI =30.2; 64.1），Pabré为45.5%（95%CI=19.0; 74.1）。在Nyonyogo没有发现NCC病例。所有确诊和可能的NCC病例均来自养猪很普遍的两个村庄。旨在减少该国癫痫负担的预防政策应包括旨在中断猪带绦虫生命周期的措施。
To estimate the lifetime prevalence of neurocysticercosis (NCC) associated epilepsy and the proportion of NCC among people with epilepsy in three Burkina Faso villages. Three villages were selected to represent three types of pig-rearing methods: 1) Batondo where pigs are left to roam; 2) Pabré where pigs are mostly tethered or penned, and 3) Nyonyogo where the majority of residents are Muslim and few pigs are raised. In Batondo and Nyonyogo, all concessions (a group of several households) were included. Half of the concessions in Pabré were randomly chosen. All households of selected concessions were included, and one person per household was randomly selected for epilepsy screening and serological testing for cysticercosis. Self-reported cases of epilepsy were also examined and confirmed cases included in analyses other than the estimate of NCC-associated epilepsy prevalence. Epilepsy was defined as ever having had more than one episode of unprovoked seizures. Medically confirmed cases of epilepsy had a computerized tomography (CT) scan of the brain before and after contrast medium injection. The diagnosis of NCC was made using a modification of the criteria of. Thirty-nine (4.4%) of 888 randomly selected villagers and 33 of 35 (94.3%) self-reported seizures cases were confirmed to have epilepsy by medical examination. Among the 68 participants with epilepsy who had a CT scan, 20 patients were diagnosed with definitive or probable NCC for a proportion of 46.9% (95% CI=30.2; 64.1) in Batondo and 45.5% (95%CI=19.0; 74.1) in Pabré. No cases of NCC were identified in Nyonyogo. All the definitive and probable cases of NCC were from the two villages where pig breeding is common. Prevention policies intended to reduce the burden of epilepsy in this country should include measures designed to interrupt the life cycle of Taenia solium.