A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients
A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients
复制标题
慢性精神分裂症患者吩噻嗪戒断的对照试验
DOI：
10.1192/bjp.128.5.451
复制
发表时间：
1976
影响因子：
10.5
通讯作者：
R. Snaith
中科院分区：
文献类型：
--
作者：
P. Andrews;J. N. Hall;R. Snaith
摘要 17 名慢性精神分裂症住院患者停用了吩噻嗪药物，对照组 14 名患者仍在积极用药。该试验在双盲条件下进行，为期 42 周，病房护士每周对患者进行评估。安慰剂组中有 35% 的人复发，复发与之前的活性药物水平有关。
Summary Phenothiazine drugs were withdrawn from 17 chronic schizophrenic in-patients, with a control group of 14 patients remaining on active medication. The trial was conducted under double blind conditions over a period of 42 weeks with weekly assessment of the patients by ward nurses. Of the placebo group 35 per cent relapsed, relapse being related to the level of previous active medication.