Vacuum-assisted closure: A new method for wound control and treatment: Clinical experience
Vacuum-assisted closure: A new method for wound control and treatment: Clinical experience
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DOI：
10.1097/00000637-199706000-00002
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发表时间：
1997-06-01
影响因子：
1.5
通讯作者：
Morykwas, MJ
中科院分区：
文献类型：
--
作者：
Argenta, LC;Morykwas, MJ
尽管取得了许多进展，但慢性和其他难以处理的伤口仍然是治疗上的挑战。提出了一种新的亚大气压封闭技术：真空辅助封闭技术。vac技术需要将开孔泡沫敷料放入伤口腔内，并施加可控的亚大气压（低于环境压力125毫米汞柱）。治疗伤口300处，其中慢性伤口175处，亚急性伤口94处，急性伤口31处。226个伤口对低气压治疗反应良好，肉芽组织形成率增加。治疗伤口直到完全闭合，用裂厚的皮肤移植物覆盖，或将皮瓣旋转到健康的肉芽化伤口床上。该技术消除了慢性水肿，导致局部血流量增加，并且施加的力导致肉芽组织的形成增强。真空辅助闭合是治疗慢性和困难伤口的一种非常有效的方式。
Despite numerous advances, chronic and other difficult-to-manage wounds continue to be a treatment challenge. Presented is a new subatmospheric pressure technique: vacuum-assisted closure (The V.A.C.). The V.A.C. technique entails placing an open-cell foam dressing into the wound cavity and applying a controlled subatmospheric pressure (125 mmHg below ambient pressure). Three hundred wounds were treated: 175 chronic wounds, 94 subacute wounds, and 31 acute wounds. Two hundred ninety-six wounds responded favorably to subatmospheric pressure treatment, with an increased rate of granulation tissue formation. Wounds were treated until completely closed, were covered with a split-thickness skin graft, or a flap was rotated into the healthy, granulating wound bed. The technique removes chronic edema, leading to increased localized blood flow, and the applied forces result in the enhanced formation of granulation tissue. Vacuum-assisted closure is an extremely efficacious modality for treating chronic and difficult wounds.