Noninvasive Evaluation of Spatial Distribution of Local Instantaneous Strain Energy in Heart Wall
Noninvasive Evaluation of Spatial Distribution of Local Instantaneous Strain Energy in Heart Wall
复制标题
心壁局部瞬时应变能空间分布的无创评估
DOI：
10.1007/978-1-4419-8588-0_30
复制
发表时间：
1997
期刊：
影响因子：
--
通讯作者：
Motonao Tanaka
中科院分区：
文献类型：
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作者：
H. Kanai;H. Hasegawa;N. Chubachi;Y. Koiwa;Motonao Tanaka
为了基于心肌声学特性的心脏疾病的非侵入性诊断，我们开发了一种用于精确跟踪心脏壁运动的新方法1。用这种方法可以在高达几百赫兹的频率范围内连续地检测到由10 mm大幅度心跳引起的心壁运动中小于10 μm的小幅度速度信号，并具有足够的重复性，持续约10次心跳。该方法已被应用于左心室壁沿着超声束2预置的多个点，从而同时获得这些点处速度的空间（深度）分布。根据得到的速度信号，心壁的运动被分为以下两个分量：心壁的平行整体运动和在心肌收缩/舒张期间在LV壁的每个深度处的心肌层增厚的变化。本文从心肌局部厚度的变化出发，无创性地评价了心肌中产生和储备的瞬时应变能的空间分布。这一新方法为无创性声学诊断心肌局部运动，即心室壁心肌层功能的研究提供了可能。
For the noninvasive diagnosis of heart disease based on the acoustic characteristics of the heart muscle, we have developed a new method1 for accurately tracking the movement of the heart wall. By this method, avelocity signalof the heart wall with a small amplitude of less than 10 µm on themotionresulting from a heartbeat with large amplitude of 10 mm can be successfully detected with sufficient reproducibility in the frequency range up to several hundred Hertz continuously for periods of about ten heartbeats. The method has been applied to multiple points preset in the left ventricular (LV) wall along the ultrasonic beam2so that the spatial (depth) distributions of the velocity at these points are simultaneously obtained. From the resultant velocity signals, the motion of the heart wall is divided into the following two components:parallel global motionof the heart wall andthe change in myocardial layer thickeningat each depth across the LV wall duringmyocardial contraction/relaxation. In this paper, from the local change in thickness, spatial distribution of instantaneous strain energy generated and reserved in myocardium is noninvasively evaluated. This new approach offers potential for research on noninvasive acoustical diagnosis ofmyocardial local motility, that is, the myocardial layer function in the ventricular wall.