Visual assessment of coronary artery stenosis with electrocardiographically-gated multislice computed tomography
Visual assessment of coronary artery stenosis with electrocardiographically-gated multislice computed tomography
复制标题
心电门控多层计算机断层扫描对冠状动脉狭窄的视觉评估
DOI：
10.1023/b:caim.0000013159.01950.7c
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
M. Horie
中科院分区：
文献类型：
--
作者：
S. Matsuo;Yasuyuki Nakamura;Tetsuya Matsumoto;I. Nakae;Y. Nagatani;R. Takazakura;Masashi Takahashi;K. Murata;M. Horie
背景资料：多层探测器计算机断层扫描（MSCT）具有更快的图像采集时间和更薄的切片宽度，可实现人体冠状动脉的可视化。随着图像质量的显著提高，高分辨率和新的三维后处理软件的出现，使得无创地检查人体内的腔体成为可能。目的：本研究的目的是评价ECG门控MSCT对冠状动脉严重狭窄和闭塞的诊断准确性。对25例疑有阻塞性冠状动脉疾病的患者（男19例，女6例，年龄65 ± 9岁），采用8层螺旋CT进行心电门控多层螺旋CT血管造影。在三个冠状动脉中模拟可视化冠状动脉。所有患者均行常规冠状动脉造影。结果：目前MSCT可以直观显示冠状动脉，图像质量良好。诊断冠状动脉明显狭窄的敏感性为75.0%，特异性为95.6%。阳性和阴性预测值分别为84.9%和92.2%。MSCT对冠状动脉狭窄的诊断准确性以左主干和左前降支最高，回旋支最低。结论：MSCT诊断冠状动脉狭窄是可行的。
Background: With faster image acquisition times and thinner slice widths, multislice detector computed tomography (MSCT) allows visualization of human coronary arteries. Significantly improved image quality, with high resolution and new software for three-dimensional post-processing, has made non-invasive examination of the cavities within human body possible.Objective: The aims of this study are to evaluate the diagnostic accuracy of ECG-gated MSCT for the detection of significant coronary artery stenosis and occlusions.Methods: In 25 patients (19 male and 6 female aged 65 ± 9 years) with suspected obstructive coronary artery disease, ECG-gated MSCT angiography was performed with an 8-slice MSCT scanner. Visual coronary arteries were simulated in three coronary arteries. Conventional coronary angio-graphies were performed in all patients. And coronary lesions in MSCT were estimated by two observers, who did not know the results of the coronary angiography.Results: Current MSCT allows visual coronary artery with good image quality. The overall sensitivity for diagnosing significant coronary stenosis were 75.0%, the specificity was 95.6%. The positive and negative predictive values were 84.9 and 92.2%, respectively. The accuracy of MSCT for detecting coronary stenosis is the highest in the left main tranck and left anterior descending coronary artery, and lowest in the circumflex coronary artery.Conclusion: MSCT was feasible for the detection of coronary artery stenosis.