RIGHT AND LEFT-VENTRICULAR FUNCTION AT REST AND WITH EXERCISE IN PATIENTS WITH SARCOIDOSIS

RIGHT AND LEFT-VENTRICULAR FUNCTION AT REST AND WITH EXERCISE IN PATIENTS WITH SARCOIDOSIS
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DOI:
10.1378/chest.85.3.301
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发表时间:
1984-01-01
期刊:
影响因子:
9.6
通讯作者:
BOSKEN, CH
BOSKEN, CH
中科院分区:
医学1区
文献类型:
--
作者:
BAUGHMAN, RP;GERSON, M;BOSKEN, CH

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对14例结节病所致限制性肺病患者进行放射性核素心血管造影研究,以确定右心室和左心室功能障碍的发生率和意义。在静息和运动时,通过平衡技术测定右心室和左心室射血分数。所有患者静息时左心室射血分数正常,14例患者中有12例患者运动时射血分数升高5%或以上。3例患者静息时右心室射血分数异常,仅2例患者运动时射血分数升高5%或以上。运动时右室射血分数与肺总容量(r = 0.73,P < 0.01)和动脉血氧分压(r = 0.74,P < 0.01)相关。
Patients (14) with restrictive pulmonary disease due to sarcoidosis were studied with radionuclide angiocardiography in order to define the incidence and significance of right and left ventricular dysfunction. Right and left ventricular ejection fractions were determined by an equilibrium technique at both rest and exercise. All patients had a normal left ventricular ejection fraction with rest and 12 of 14 had the normal 5% or greater rise in ejection fraction with exercise. The right ventricular ejection fraction was abnormal in 3 patients at rest and only 2 patients had a 5% or greater rise in ejection fraction with exercise. A correlation was found between the right ventricular ejection fraction with exercise and the total lung capacity (r = 0.73, P < 0.01) and the arterial PO2 during exercise (r = 0.74, P < 0.01).