Predicting physical and chemical properties of bioactive glasses from chemical composition. Part 3: In vitro reactivity
Predicting physical and chemical properties of bioactive glasses from chemical composition. Part 3: In vitro reactivity
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从化学成分预测生物活性玻璃的物理和化学性质。
DOI：
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发表时间：
2009
期刊：
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通讯作者：
M. Hupa
中科院分区：
文献类型：
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作者：
Di Zhang;E. Vedel;L. Hupa;H. Aro;M. Hupa
研究了Na2O-K2O-MgO-CaO-B2O-P2O5-SiO2系统玻璃在模拟体液(SBF)中4~168h的体外行为，测定了SBF中硅酸盐、钙、磷离子的浓度和pH值，并测量了玻璃的失重与浸泡时间的关系。用扫描电子显微镜/能谱分析研究了玻璃表面形成的表面层。溶液和玻璃上的变化被描述为玻璃的氧化物组成的函数。结果表明，通过考虑SBF和玻璃本身在浸泡过程中的一些性质的变化，可以根据玻璃的化学成分对生物活性玻璃的体外反应性进行合理的估计。
In vitro behaviour of thirty glasses in the system Na 2 O―K 2 O―MgO―CaO―B 2 O 3 ―P 2 O 5 ―SiO 2 was studied in simulated body fluid (SBF) for 4 to 168 h. Concentrations of silicate, calcium and phosphate ions and pH in SBF were determined and weight loss of the glasses was measured as a function of immersion time. The surface layers formed on the glasses were studied with SEM/EDXA. The changes in the solution and on the glass were described as functions of the oxide composition of the glass. The results show that by taking into account changes of several properties of the SBF and the glass itself during immersion, a sound estimation of the in vitro reactivity of bioactive glasses can be obtained based on chemical composition of the glass.