ROLE OF FRONTIER ORBITALS IN CHEMICAL-REACTIONS
ROLE OF FRONTIER ORBITALS IN CHEMICAL-REACTIONS
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DOI：
10.1126/science.218.4574.747
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发表时间：
1982-01-01
期刊：
影响因子：
56.9
通讯作者：
FUKUI, K
中科院分区：
文献类型：
--
作者：
FUKUI, K
因此，Naapht~alene中的亲电取代反应，如硝化反应，生成α-取代衍生物Predo~，就不那么容易回答了。这是因为，许多这种未被取代的芳香烃，亲水性和亲核性都在同一位置反应。这一点让人们对有机反应性理论产生了一些怀疑，在有机反应性理论中，电子密度被认为决定了一切。
Kenichi Fuk~ i fore, the electrophilic substitution in napht~ alene, for instance, such as nitration, yields a-substituted derivatives predo~ inantly was not so easy to answer. That was because, i~ many of such unsubstituted aromatic hydrocarbons, both the electrophile and the nucleophile react at the same location. This point threw some doubt on the theory of organic reactivity, where the electron density was thought to do everything.