Somatomedin Activity and Diabetic Control in Children with Insulin-Dependent Diabetes
Somatomedin Activity and Diabetic Control in Children with Insulin-Dependent Diabetes
复制标题
胰岛素依赖型糖尿病儿童的生长调节素活性和糖尿病控制
作者：
R. Winter;L. Phillips;Mordecai N Klein;H. Traisman;O. Green
为了验证生长激素活性受糖尿病及其代谢调节的影响这一假说，我们对40例胰岛素依赖型糖尿病儿童进行了生长激素活性与糖化血红蛋白A1C评估的糖尿病控制关系的研究。血红蛋白A1c与血清生长抑素活性呈显著负相关。这些数据表明，在糖尿病控制不佳的儿童中可能发生的线性生长异常，可能与净生长素活动异常有关。
To test the hypothesis that somatomedin activity is influenced by diabetes and its metabolic regulation, the relationship between somatomedin activity and diabetic control as assessed by hemoglobin A1C was investigated in 40 children with insulin-dependent diabetes. An inverse correlation between hemoglobin A1c and serum somatomedin activity was statistically significant. The data suggest that abnormalities of linear growth, which can occur in children with poorly controlled diabetes, may involve abnormalities in net somatomedin activity.