EXPERIMENTAL SACCULAR ANEURYSMS .2. A NEW MODEL IN SWINE
EXPERIMENTAL SACCULAR ANEURYSMS .2. A NEW MODEL IN SWINE
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DOI：
10.1007/bf00593518
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发表时间：
1994-10-01
期刊：
影响因子：
2.8
通讯作者：
ROBERT, J
中科院分区：
文献类型：
--
作者：
GUGLIELMI, G;JI, C;ROBERT, J
描述了一种在猪颈总动脉上手术构建实验性外侧囊状动脉瘤的新技术。它涉及将一段孤立的静脉端侧缝合到动脉上。在短暂的载瘤动脉夹闭期间，通过开口静脉移植物形成椭圆形动脉切开术，随后将其开口端打结并除去湿气，形成动脉瘤静脉袋。该技术的主要优点是隔离载瘤动脉段所需的血管阻尼时间较短。这可以防止严重的内皮损伤和长时间的术后血管痉挛，这两者都可能促进动脉瘤内血栓形成。可以产生窄颈或宽颈动脉瘤。详细介绍了该模型的手术构建步骤，并强调了使用猪的具体优势。
A new technique for surgical construction of experimental lateral saccular aneurysms on the common carotid artery of swine is described. It involves end-to-side suturing of an isolated segment of vein to an artery. During a short period of parent artery clamping, an elliptical arteriotomy is fashioned through the open-ended vein graft, the open end of which is subsequently tied and damps are removed to form an aneurysmal vein pouch. The principal advantage of this technique is the short period of vascular damping necessary to isolate a segment of the parent artery. This prevents severe endothelial injury and prolonged postoperative vasospasm, both of which may promote intra-aneurysmal thrombosis. Narrow- or wide-necked aneurysms can be created. Steps in the surgical construction of this model are detailed, and specific advantages of using swine are highlighted.