Fetal heart rate and variability: Stability and prediction to developmental outcomes in early childhood
Fetal heart rate and variability: Stability and prediction to developmental outcomes in early childhood
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DOI：
10.1111/j.1467-8624.2007.01099.x
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发表时间：
2007-12-01
影响因子：
4.6
通讯作者：
Achy-Brou, Aristide
中科院分区：
文献类型：
--
作者：
DiPietro, Janet A.;Costigan, Kathleen;Achy-Brou, Aristide
出生前心脏指标的稳定性及其在预测出生后发育变化中的实用性进行了检查。胎儿心率和变异性纵向测量从20至38周妊娠（n = 137），并再次在2岁（n = 79）。显着的个体内的稳定性在产前期间，并进入儿童期被证明。在妊娠28周或之后的胎儿心率变异性和陡峭的发育轨迹与2岁时的智力和精神发育（n = 82）和2.5岁时的语言能力（n = 61）显著相关。这些数据表明，自主控制的个体差异的基础起源于妊娠期和胎儿期的发育势头继续出生后。
Stability in cardiac indicators before birth and their utility in predicting variation in postnatal development were examined. Fetal heart rate and variability were measured longitudinally from 20 through 38 weeks gestation (n = 137) and again at age 2 (n = 79). Significant within-individual stability during the prenatal period and into childhood was demonstrated. Fetal heart rate variability at or after 28 weeks gestation and steeper developmental trajectories were significantly associated with mental and psychomotor development at 2 years (n = 82) and language ability at 2.5 years (n = 61). These data suggest that the foundations of individual differences in autonomic control originate during gestation and the developmental momentum of the fetal period continues after birth.