Stadienspezifische Aggregationsmuster bei Dictyostelium discoideum.
Stadienspezifische Aggregationsmuster bei Dictyostelium discoideum.
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DOI：
10.1007/bf00573870
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发表时间：
1965-01-01
影响因子：
--
通讯作者：
Gerisch, G.
中科院分区：
文献类型：
--
作者：
Gerisch, G.
1. 在悬浮培养物中生长的盘基网柄菌细胞紧密堆积，形成聚集模式，其特定结构反映了细胞的功能状态。 2. 在这些结构形成之前，会出现激发波，其传播速度约为 40μ/min。如果作为一个整体有节奏地发挥作用，波传播中心就会产生一个由单独的同心波组成的系统。相反，如果中心的部分区域相继变得活跃，则形成连续的螺旋形激励前沿。 3.有人提出，与自节律中心相关的传播波抑制其附近类似中心的形成（“间隔效应”）。 4.由紧密堆积的细胞形成的聚集体通常太大而不能产生单个子实体。在这种情况下，一种分裂细胞团的机制被激活；由此产生的每个部分都会将自己转变为一个果皮。
1. Closely packed cells ofDictyostelium discoideum, grown in a suspension culture, form aggregation patterns whose specific structures reflect the functional states of the cells. 2. Prior to the development of these structures, waves of excitation appear which propagate with a velocity of about 40μ/min. If functioning rhythmically as a whole, the wave-propagating center gives rise to a system of separate, concentric waves. If, on the contrary, parts of the center become active successively, a continuous spiralshaped excitation front is formed. 3. It is proposed, that the propagated waves associated with an autorhythmic center inhibit the formation of similar centers in its vicinity (" spacing effect"). 4. The aggregates formed by the closely packed cells are often too large to give rise to a single sorocarp. In this case a mechanism becomes active which divides the cell mass; each of the resulting parts transforms itself into a sorocarp.