The ROCK signaling and breast cancer metastasis

The ROCK signaling and breast cancer metastasis
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DOI:
10.1007/s11033-010-0238-4
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发表时间:
2011-02-01
影响因子:
2.8
通讯作者:
Liu, Sijin
Liu, Sijin
中科院分区:
生物学4区
文献类型:
--
作者:
Liu, Sijin

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Metastasis is the predominant cause of death in most breast cancer patients. The molecular mechanisms underlying metastasis from primary tumors to distant organs are not clearly characterized. In this review, we depict the role of ROCK signaling in regulating cell motility and growth, and discuss the contribution of this signaling to breast cancer metastasis.