Comparative psychological disturbance in patients with pancreatic and gastric cancer.

Comparative psychological disturbance in patients with pancreatic and gastric cancer.
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DOI:
10.1176/ajp.143.8.982
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发表时间:
1986-08
期刊:
The American journal of psychiatry
影响因子:
--
通讯作者:
J. Holland;A. Korzun;S. Tross;P. Silberfarb;M. Perry;R. Comis;M. Oster
J. Holland;A. Korzun;S. Tross;P. Silberfarb;M. Perry;R. Comis;M. Oster
中科院分区:
其他
文献类型:
--
作者:
J. Holland;A. Korzun;S. Tross;P. Silberfarb;M. Perry;R. Comis;M. Oster

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107例晚期胰腺癌患者和111例晚期胃癌患者,在开始联合化疗前,在国家癌症临床试验组中使用情绪状态特征对关键医学和社会人口学变量进行分层。胰腺癌患者的抑郁、紧张焦虑、疲劳、困惑困惑和总情绪障碍的自评显著高于对照组,而活力和愤怒敌意的自评差异无统计学意义。这些数据支持先前的观察,即晚期胰腺癌患者的一般心理障碍明显大于其他类型的晚期腹部肿瘤患者。
One hundred and seven patients with advanced pancreatic cancer and 111 patients with advanced gastric cancer, stratified for key medical and sociodemographic variables, were assessed with the Profile of Mood States before beginning combination chemotherapy in a national cancer clinical trials group. The pancreatic cancer patients had significantly higher self-ratings of depression, tension-anxiety, fatigue, confusion-bewilderment, and total mood disturbance; no difference was found in vigor or anger-hostility. These data support prior observations that patients with advanced pancreatic cancer experience significantly greater general psychological disturbance than patients with another type of advanced abdominal neoplasm.