Isolation of 2-Pyridone Alkaloids from a New Zealand Marine-Derived Penicillium species

Isolation of 2-Pyridone Alkaloids from a New Zealand Marine-Derived Penicillium species
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DOI:
10.1021/np800627f
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发表时间:
2009-03-01
影响因子:
5.1
通讯作者:
Munro, Murray H. G.
Munro, Murray H. G.
中科院分区:
生物学2区
文献类型:
--
作者:
de Silva, E. Dilip;Geiermann, Anna-Skrollan;Munro, Murray H. G.

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从新西兰奥塔哥的Macrocarpa Point采集的棕色剑尾鱼的表面灭菌的叶状体片段中分离的青霉菌在半浓度马铃薯葡萄糖肉汤中发酵,导致三种生物碱的分离和表征:已知的N-羟基-2-吡啶酮,PF 1140(1),和两种新的2-吡啶酮,2和3。
Fermentation of a Penicillium sp. isolated from a surface-sterilized thallus segment of the brown alga Xiphophora gladiata, collected from Macrocarpa Point, Otago, New Zealand, in half-strength potato dextrose broth led to the isolation and characterization of three alkaloids: the known N-hydroxy-2-pyridone, PF1140 (1), and two new 2-pyridones, 2 and 3.