Scintimammography with 99mTc-MIBI versus dynamic MRI for non-invasive characterization of breast masses
Scintimammography with 99mTc-MIBI versus dynamic MRI for non-invasive characterization of breast masses
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99mTc-MIBI 闪烁乳房X线照相术与动态MRI对比用于乳腺肿块的非侵入性表征
DOI：
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
A. Sodano
中科院分区：
文献类型：
--
作者：
M. Imbriaco;S. Del Vecchio;A. Riccardi;L. Pace;F. Di Salle;F. Di Gennaro;M. Salvatore;A. Sodano
抽象的。虽然乳房X光照相仍是早期发现乳腺癌的首选技术，但包括核素扫描和磁共振成像(MRI)在内的几种成像技术最近已被提出作为这一目的的辅助手段，并包括在许多诊断方案中。本研究旨在评价99m-甲氧基异丁基异腈(MIBI)核素显像和增强MRI对钼靶X线表现可疑的乳腺癌的诊断价值。对49名通过体检或乳房X光摄影和超声(US)发现可疑乳腺肿块的患者进行了研究。所有患者均间隔1周行核素扫描和动态增强MRI检查。将两种技术的结果进行比较，并与最终诊断相关联。两名独立读者报告了使用四分置信度标准进行的扫描。得到了受试者操作员特征(ROC)曲线下面积。核素扫描对肿瘤诊断的准确率为84%，灵敏度为80%，特异度为88%。MRI诊断准确率为86%，敏感性为96%，特异性为75%。两组ROC曲线下面积比较，MRI为0.91±0.05(平均值±SD)，核素扫描为0.88±0.05(P=0.9)。结论动态核磁共振和核素扫描对钼靶或超声检查可疑的乳腺癌患者具有相同的诊断准确性。
Abstract. Although mammography remains the technique of choice for the early detection of breast cancer, several imaging techniques, including scintimammography and magnetic resonance imaging (MRI), have recently been proposed as adjuncts for this purpose and included in many diagnostic protocols. This study was undertaken to assess the clinical accuracy of scintimammography with technetium-99m methoxyisobutylisonitrile (MIBI) and contrast-enhanced MRI in the detection of primary breast carcinoma in patients with equivocal mammographic findings. Forty-nine patients with a suspicious breast mass detected either by physical examination or by mammography and ultrasound (US) were studied. All patients underwent scintimammography and dynamic contrast-enhanced MRI 1 week apart. The results of the two techniques were compared and correlated to the final diagnoses. Two independent readers reported the scans using a four-point confidence scale. The areas under the receiver operator characteristic (ROC) curves were obtained. Scintimammography showed an accuracy for tumour detection of 84%, with a sensitivity of 80% and a specificity of 88%. MRI showed an accuracy of 86%, with a sensitivity and specificity of 96% and 75%, respectively. Comparison of the two areas under the ROC curves showed no significant differences between MRI, 0.91±0.05 (mean±SD), and scintimammography, 0.88±0.05 (P=0.9). It is concluded that dynamic MRI and scintimammography possess comparable accuracy in the diagnosis of primary breast carcinoma in patients with equivocal mammographic or US findings.
乳腺X线摄影引导下不可触及乳腺病变的细针抽吸活检的现状。
影响因子：
1.9
作者：
Jackson,VP
通讯作者：
Jackson,VP
DOI：
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发表时间：
1990-10
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
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作者：
M. L. Chiu;J. Kronauge;D. Piwnica-worms
通讯作者：
M. L. Chiu;J. Kronauge;D. Piwnica-worms