Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation.
Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation.
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PP2A-B56α 异质复合物的激活通过 BCL2 和 MCL1 调节与 AML 中的 Venetoclax 疗法产生协同作用。
DOI:
10.1182/blood.2022016466
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发表时间:
2023
期刊:
影响因子:
20.3
通讯作者:
Mateos,Ma
中科院分区:
文献类型:
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作者:
Peris,Irene;Romero-Murillo,Silvia;Martínez-Balsalobre,Elena;Farrington,CarolineC;Arriazu,Elena;Marcotegui,Nerea;Jiménez-Muñoz,Marta;Alburquerque-Prieto,Cristina;Torres-López,Andrea;Fresquet,Vicente;Martínez-Climent,JoseA;Mateos,Ma