Genotyping of Entamoeba species in South Africa: diversity, stability, and transmission patterns within families.

Genotyping of Entamoeba species in South Africa: diversity, stability, and transmission patterns within families.
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南非内阿米巴物种的基因分型:多样性、稳定性和科内传播模式。

DOI:
10.1086/375349
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发表时间:
2003
期刊:
The Journal of infectious diseases.
影响因子:
--
通讯作者:
Clark,CGraham
Clark,CGraham
中科院分区:
--
文献类型:
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作者:
Zaki,Mehreen;Reddy,SelvanG;Jackson,TerryFHG;Ravdin,JonathanI;Clark,CGraham

文献摘要

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使用最近描述的基于聚合酶链反应的 DNA 分型方法来检测溶组织内阿米巴和大肠杆菌。 disparwe 在南非的一个地理限制区域调查了这些物种的遗传多样性。同一感染的模式随着时间的推移是稳定的,并且除了少数例外,受感染的家庭成员携带相同的菌株。然而,这两个物种都表现出显着的变异,没有两个科群感染同一株大肠杆菌。溶组织病。混合感染很少见。结果表明,这种分型方法将有助于确定感染之间的流行病学联系
Using a recently described polymerase chain reaction–based DNA typing method forEntamoeba histolyticaandE. disparwe investigated the genetic diversity of these species in a geographically restricted region of South Africa. Patterns were stable over time in the same infection, and, with few exceptions, infected family members carried the same strain. However, both species exhibited remarkable variation, with no 2 family groups being infected with the same strain ofE. histolytica. Mixed infections were rare. The results indicate that this typing method will be useful in identifying epidemiological linkage between infections