Genotyping of Entamoeba species in South Africa: diversity, stability, and transmission patterns within families.
Genotyping of Entamoeba species in South Africa: diversity, stability, and transmission patterns within families.
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南非内阿米巴物种的基因分型:多样性、稳定性和科内传播模式。
DOI:
10.1086/375349
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发表时间:
2003
期刊:
影响因子:
--
通讯作者:
Clark,CGraham
中科院分区:
文献类型:
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作者:
Zaki,Mehreen;Reddy,SelvanG;Jackson,TerryFHG;Ravdin,JonathanI;Clark,CGraham
Using a recently described polymerase chain reaction–based DNA typing method forEntamoeba histolyticaandE. disparwe investigated the genetic diversity of these species in a geographically restricted region of South Africa. Patterns were stable over time in the same infection, and, with few exceptions, infected family members carried the same strain. However, both species exhibited remarkable variation, with no 2 family groups being infected with the same strain ofE. histolytica. Mixed infections were rare. The results indicate that this typing method will be useful in identifying epidemiological linkage between infections