Gaze but not arrows: A dissociative impairment after right superior temporal gyrus damage
Gaze but not arrows: A dissociative impairment after right superior temporal gyrus damage
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DOI：
10.1016/j.neuropsychologia.2006.03.007
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发表时间：
2006-01-01
期刊：
影响因子：
2.6
通讯作者：
Kashima, Haruo
中科院分区：
文献类型：
--
作者：
Akiyama, Tomoko;Kato, Motoichiro;Kashima, Haruo
在正常大脑中，当观察眼睛时，一直显示出颞上沟(STS)的激活，因此，这一区域被认为是人类的凝视处理区。在最近的一份报告中，我们提出了一个病例，M.J.，右颞上回(STG)有一个界限清楚的病变，表现出对凝视方向的辨别能力受损。为了明确这种损害是否是凝视独有的，我们应用了Kingstone和他的同事建立的空间线索范式。在我们的实验中，图像凝视和对称箭头被集中呈现为检测外围目标的非预测性空间线索。15名正常受试者和M.J.参加了实验。与以前的报道一致的是，与不一致的线索相比，控制组在检测一致的凝视/箭头线索的目标时表现出显著的反应时促进。与之形成鲜明对比的是，面对正常的射箭一致性优势，M.J.在凝视方面没有表现出这样的一致性优势。我们已经证明，右侧STG的局限性损害了利用生物方向信息(如凝视)的能力，但保留了非生物对应物(箭头)的完整。这种分离意味着STS实际上是专门处理凝视的。(C)2006爱思唯尔有限公司。保留所有权利。
Superior temporal sulcus (STS) activation has consistently been demonstrated in the normal brain when viewing eyes, and thus this area is implicated as a gaze processing region in humans. In a recent report, we have presented a case, M.J., with a well-circumscribed lesion to the right superior temporal gyrus (STG), who demonstrated impaired discrimination of gaze direction. In the aim to make distinct whether this impairment is unique to gaze, we have applied a spatial cueing paradigm established by Kingstone and Colleagues. In our experiment, pictorial gaze and symmetrical arrows were centrally presented as non-predictive, spatial cues in detecting peripheral targets. Fifteen normal subjects and M.J. participated in the experiment. In concordance with previous reports, controls demonstrated a significant facilitation of reaction times in detecting targets cued by congruent gaze/arrows, compared with incongruent cues. In striking contrast, M.J. showed no such congruency advantage for gaze, in the face of a normal congruency advantage for arrows. We have demonstrated that a circumscribed lesion to the right STG impairs the ability to utilize biological directional information such as gaze, but leaves the non-biological counterpart (arrows) intact. This dissociation implies that indeed, the STS specializes in processing gaze. (c) 2006 Elsevier Ltd. All rights reserved.